A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication.

Herpes simplex virus type 1 (HSV-1) is a neurotropic virus causing vesicular oral or genital skin lesions, meningitis and other diseases particularly harmful in immunocompromised individuals. To comprehensively investigate the complex interaction between HSV-1 and its host we combined two genome-sca...

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Autores principales:	Samantha J Griffiths, Manfred Koegl, Chris Boutell, Helen L Zenner, Colin M Crump, Francesca Pica, Orland Gonzalez, Caroline C Friedel, Gerald Barry, Kim Martin, Marie H Craigon, Rui Chen, Lakshmi N Kaza, Even Fossum, John K Fazakerley, Stacey Efstathiou, Antonio Volpi, Ralf Zimmer, Peter Ghazal, Jürgen Haas
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Immunologic diseases. Allergy RC581-607 Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/c1319d0c08484c8a870675e878702559
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A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication.

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