A serum microRNA classifier for the diagnosis of sarcomas of various histological subtypes

Sarcomas are rare malignant tumours of bone and soft tissue whose diagnosis remain difficult. Here, the authors analyse serum samples from over 1000 patients and using separate discovery, training and validation cohorts, identify and validate a 7-microRNA index that distinguishes malignant sarcomas...

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Autores principales:	Naofumi Asano, Juntaro Matsuzaki, Makiko Ichikawa, Junpei Kawauchi, Satoko Takizawa, Yoshiaki Aoki, Hiromi Sakamoto, Akihiko Yoshida, Eisuke Kobayashi, Yoshikazu Tanzawa, Robert Nakayama, Hideo Morioka, Morio Matsumoto, Masaya Nakamura, Tadashi Kondo, Ken Kato, Naoto Tsuchiya, Akira Kawai, Takahiro Ochiya
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c1326b7ed5784af3b902e9252e2a82b8
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spelling	oai:doaj.org-article:c1326b7ed5784af3b902e9252e2a82b82021-12-02T16:50:57ZA serum microRNA classifier for the diagnosis of sarcomas of various histological subtypes10.1038/s41467-019-09143-82041-1723https://doaj.org/article/c1326b7ed5784af3b902e9252e2a82b82019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09143-8https://doaj.org/toc/2041-1723Sarcomas are rare malignant tumours of bone and soft tissue whose diagnosis remain difficult. Here, the authors analyse serum samples from over 1000 patients and using separate discovery, training and validation cohorts, identify and validate a 7-microRNA index that distinguishes malignant sarcomas from benign disease.Naofumi AsanoJuntaro MatsuzakiMakiko IchikawaJunpei KawauchiSatoko TakizawaYoshiaki AokiHiromi SakamotoAkihiko YoshidaEisuke KobayashiYoshikazu TanzawaRobert NakayamaHideo MoriokaMorio MatsumotoMasaya NakamuraTadashi KondoKen KatoNaoto TsuchiyaAkira KawaiTakahiro OchiyaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Naofumi Asano Juntaro Matsuzaki Makiko Ichikawa Junpei Kawauchi Satoko Takizawa Yoshiaki Aoki Hiromi Sakamoto Akihiko Yoshida Eisuke Kobayashi Yoshikazu Tanzawa Robert Nakayama Hideo Morioka Morio Matsumoto Masaya Nakamura Tadashi Kondo Ken Kato Naoto Tsuchiya Akira Kawai Takahiro Ochiya A serum microRNA classifier for the diagnosis of sarcomas of various histological subtypes
description	Sarcomas are rare malignant tumours of bone and soft tissue whose diagnosis remain difficult. Here, the authors analyse serum samples from over 1000 patients and using separate discovery, training and validation cohorts, identify and validate a 7-microRNA index that distinguishes malignant sarcomas from benign disease.
format	article
author	Naofumi Asano Juntaro Matsuzaki Makiko Ichikawa Junpei Kawauchi Satoko Takizawa Yoshiaki Aoki Hiromi Sakamoto Akihiko Yoshida Eisuke Kobayashi Yoshikazu Tanzawa Robert Nakayama Hideo Morioka Morio Matsumoto Masaya Nakamura Tadashi Kondo Ken Kato Naoto Tsuchiya Akira Kawai Takahiro Ochiya
author_facet	Naofumi Asano Juntaro Matsuzaki Makiko Ichikawa Junpei Kawauchi Satoko Takizawa Yoshiaki Aoki Hiromi Sakamoto Akihiko Yoshida Eisuke Kobayashi Yoshikazu Tanzawa Robert Nakayama Hideo Morioka Morio Matsumoto Masaya Nakamura Tadashi Kondo Ken Kato Naoto Tsuchiya Akira Kawai Takahiro Ochiya
author_sort	Naofumi Asano
title	A serum microRNA classifier for the diagnosis of sarcomas of various histological subtypes
title_short	A serum microRNA classifier for the diagnosis of sarcomas of various histological subtypes
title_full	A serum microRNA classifier for the diagnosis of sarcomas of various histological subtypes
title_fullStr	A serum microRNA classifier for the diagnosis of sarcomas of various histological subtypes
title_full_unstemmed	A serum microRNA classifier for the diagnosis of sarcomas of various histological subtypes
title_sort	serum microrna classifier for the diagnosis of sarcomas of various histological subtypes
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/c1326b7ed5784af3b902e9252e2a82b8
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A serum microRNA classifier for the diagnosis of sarcomas of various histological subtypes

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