The Impact of Acquired Genetic Abnormalities on the Clinical Translation of Human Pluripotent Stem Cells

Human pluripotent stem cells (hPSC) are known to acquire chromosomal abnormalities, which range from point mutations to large copy number changes, including full chromosome aneuploidy. These aberrations have a wide-ranging influence on the state of cells, in both the undifferentiated and differentia...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Alexander Keller, Claudia Spits
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
Accès en ligne:https://doaj.org/article/c1395ae971c647e58b863346787b5d7c
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!