FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression
Puan and San Luis et al. find that FUT6, encoding a fucosyltransferase, is required for the “rolling” behavior of certain white blood cells that enables them to move from blood vessels to tissues. They show that FUT6 deficiency leads to a loss of the tetrasaccharide sLex on the surface of basophils,...
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Main Authors: | , , , , , , , , , , , , , , , , , , , |
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Format: | article |
Language: | EN |
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Nature Portfolio
2021
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Online Access: | https://doaj.org/article/c143d737821c4b528b01c70d7893f2f4 |
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