Associations among Farm, Breed, Lactation Stage and Parity, Gene Polymorphisms and the Fatty Acid Profile of Milk from Holstein, Simmental and Their Crosses

Associations among Farm, Breed, Lactation Stage and Parity, Gene Polymorphisms and the Fatty Acid Profile of Milk from Holstein, Simmental and Their Crosses

This study aimed to analyze the factors affecting the fatty acid (FA) profile in cow’s milk. The effects of a farm, lactation parity and stage, breed and polymorphisms in the <i>AGPAT6</i>, <i>DGAT1</i>, <i>LEP</i>, <i>FASN</i> and <i>SCD1</i&...

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Autores principales: Eva Samková, Jindřich Čítek, Michaela Brzáková, Oto Hanuš, Libor Večerek, Eva Jozová, Irena Hoštičková, Jan Trávníček, Lucie Hasoňová, Michael Rost, Karolína Hálová, Jiří Špička
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
milk fatty acids
genetic and non-genetic factors
<i>AGPAT6</i>
<i>DGAT1</i>
<i>LEP</i>
<i>FASN</i>
Veterinary medicine
SF600-1100
Zoology
QL1-991
Acceso en línea:https://doaj.org/article/c146533889154e84bd8b475bb380e408
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spelling oai:doaj.org-article:c146533889154e84bd8b475bb380e4082021-11-25T16:20:31ZAssociations among Farm, Breed, Lactation Stage and Parity, Gene Polymorphisms and the Fatty Acid Profile of Milk from Holstein, Simmental and Their Crosses10.3390/ani111132842076-2615https://doaj.org/article/c146533889154e84bd8b475bb380e4082021-11-01T00:00:00Zhttps://www.mdpi.com/2076-2615/11/11/3284https://doaj.org/toc/2076-2615This study aimed to analyze the factors affecting the fatty acid (FA) profile in cow’s milk. The effects of a farm, lactation parity and stage, breed and polymorphisms in the <i>AGPAT6</i>, <i>DGAT1</i>, <i>LEP</i>, <i>FASN</i> and <i>SCD1</i> genes were evaluated. A total of 196 Holstein cows, 226 Simmental cows and seven crosses were sampled 751 times. The cows were kept at five farms and were in the first up to the sixth lactation, and 49 individual FAs and 11 groups were analyzed. The farm significantly affected the proportion of all FAs except for C16:1n-7<i>c</i> and <i>iso</i>C14:0. Additionally, the lactation stage was significant for most FAs, and the opposite was true for lactation parity. The effect of the breed was negligible. For the gene polymorphisms, the <i>SCD1</i> <i>TT</i> genotype exceeded the <i>CC</i> in C10:0, C12:0, C14:0, C16:1n-7<i>c</i> and C18:2, and the opposite was true for C10:1, C12:1, C14:1n-5<i>c</i>, <i>iso</i>C17:0, C16:1 and C18:1, i.e., the <i>TT</i> genotype was higher for saturated FAs, and the <i>CT</i> genotype was higher for monounsaturated FAs. The results hint at the intermediary heredity of the <i>SCD1</i> gene. The <i>FASN</i> gene was strongly associated with four FAs and branched-chain FAs, and genotype <i>AG</i> was better than <i>GG</i>. <i>LEP</i> was significant for five individual FAs and branched-chain FAs. The differences in FA composition among genotypes were rather small, which could lead to overestimation of the effect and needs to be considered in the next research.Eva SamkováJindřich ČítekMichaela BrzákováOto HanušLibor VečerekEva JozováIrena HoštičkováJan TrávníčekLucie HasoňováMichael RostKarolína HálováJiří ŠpičkaMDPI AGarticlemilk fatty acidsgenetic and non-genetic factors<i>AGPAT6</i><i>DGAT1</i><i>LEP</i><i>FASN</i>Veterinary medicineSF600-1100ZoologyQL1-991ENAnimals, Vol 11, Iss 3284, p 3284 (2021)
institution DOAJ
collection DOAJ
language EN
topic milk fatty acids
genetic and non-genetic factors
<i>AGPAT6</i>
<i>DGAT1</i>
<i>LEP</i>
<i>FASN</i>
Veterinary medicine
SF600-1100
Zoology
QL1-991
spellingShingle milk fatty acids
genetic and non-genetic factors
<i>AGPAT6</i>
<i>DGAT1</i>
<i>LEP</i>
<i>FASN</i>
Veterinary medicine
SF600-1100
Zoology
QL1-991
Eva Samková
Jindřich Čítek
Michaela Brzáková
Oto Hanuš
Libor Večerek
Eva Jozová
Irena Hoštičková
Jan Trávníček
Lucie Hasoňová
Michael Rost
Karolína Hálová
Jiří Špička
Associations among Farm, Breed, Lactation Stage and Parity, Gene Polymorphisms and the Fatty Acid Profile of Milk from Holstein, Simmental and Their Crosses
description This study aimed to analyze the factors affecting the fatty acid (FA) profile in cow’s milk. The effects of a farm, lactation parity and stage, breed and polymorphisms in the <i>AGPAT6</i>, <i>DGAT1</i>, <i>LEP</i>, <i>FASN</i> and <i>SCD1</i> genes were evaluated. A total of 196 Holstein cows, 226 Simmental cows and seven crosses were sampled 751 times. The cows were kept at five farms and were in the first up to the sixth lactation, and 49 individual FAs and 11 groups were analyzed. The farm significantly affected the proportion of all FAs except for C16:1n-7<i>c</i> and <i>iso</i>C14:0. Additionally, the lactation stage was significant for most FAs, and the opposite was true for lactation parity. The effect of the breed was negligible. For the gene polymorphisms, the <i>SCD1</i> <i>TT</i> genotype exceeded the <i>CC</i> in C10:0, C12:0, C14:0, C16:1n-7<i>c</i> and C18:2, and the opposite was true for C10:1, C12:1, C14:1n-5<i>c</i>, <i>iso</i>C17:0, C16:1 and C18:1, i.e., the <i>TT</i> genotype was higher for saturated FAs, and the <i>CT</i> genotype was higher for monounsaturated FAs. The results hint at the intermediary heredity of the <i>SCD1</i> gene. The <i>FASN</i> gene was strongly associated with four FAs and branched-chain FAs, and genotype <i>AG</i> was better than <i>GG</i>. <i>LEP</i> was significant for five individual FAs and branched-chain FAs. The differences in FA composition among genotypes were rather small, which could lead to overestimation of the effect and needs to be considered in the next research.
format article
author Eva Samková
Jindřich Čítek
Michaela Brzáková
Oto Hanuš
Libor Večerek
Eva Jozová
Irena Hoštičková
Jan Trávníček
Lucie Hasoňová
Michael Rost
Karolína Hálová
Jiří Špička
author_facet Eva Samková
Jindřich Čítek
Michaela Brzáková
Oto Hanuš
Libor Večerek
Eva Jozová
Irena Hoštičková
Jan Trávníček
Lucie Hasoňová
Michael Rost
Karolína Hálová
Jiří Špička
author_sort Eva Samková
title Associations among Farm, Breed, Lactation Stage and Parity, Gene Polymorphisms and the Fatty Acid Profile of Milk from Holstein, Simmental and Their Crosses
title_short Associations among Farm, Breed, Lactation Stage and Parity, Gene Polymorphisms and the Fatty Acid Profile of Milk from Holstein, Simmental and Their Crosses
title_full Associations among Farm, Breed, Lactation Stage and Parity, Gene Polymorphisms and the Fatty Acid Profile of Milk from Holstein, Simmental and Their Crosses
title_fullStr Associations among Farm, Breed, Lactation Stage and Parity, Gene Polymorphisms and the Fatty Acid Profile of Milk from Holstein, Simmental and Their Crosses
title_full_unstemmed Associations among Farm, Breed, Lactation Stage and Parity, Gene Polymorphisms and the Fatty Acid Profile of Milk from Holstein, Simmental and Their Crosses
title_sort associations among farm, breed, lactation stage and parity, gene polymorphisms and the fatty acid profile of milk from holstein, simmental and their crosses
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/c146533889154e84bd8b475bb380e408
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