Could lysine supplementation prevent Alzheimer’s dementia? A novel hypothesis
Robert N RubeyRetired, Red Lodge, Montana, USAAbstract: There is a growing body of evidence that implicates the herpes simplex type 1 virus (HSV-1) in the development of Alzheimer’s dementia (AD). HSV-1 has been found to be present in the cerebrum of the great majority of older adults,...
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Dove Medical Press
2010
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oai:doaj.org-article:c148f4d35b4848958bcd7e60a007ec432021-12-02T01:17:12ZCould lysine supplementation prevent Alzheimer’s dementia? A novel hypothesis1176-63281178-2021https://doaj.org/article/c148f4d35b4848958bcd7e60a007ec432010-10-01T00:00:00Zhttp://www.dovepress.com/could-lysine-supplementation-prevent-alzheimerrsquos-dementia-a-novel--a5555https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Robert N RubeyRetired, Red Lodge, Montana, USAAbstract: There is a growing body of evidence that implicates the herpes simplex type 1 virus (HSV-1) in the development of Alzheimer’s dementia (AD). HSV-1 has been found to be present in the cerebrum of the great majority of older adults, and in many of the same areas of the brain that are affected by AD. When active, the virus may contribute to the formation of the neurofibrillary tangles and amyloid plaques characteristic of AD. Like AD, HSV-1 encephalitis may cause long term memory loss. HSV-1 replication is suppressed in lysine-rich/arginine – poor environments, and population studies suggest that diets high in lysine and low in arginine may be associated with lower rates of AD. There are no prospective studies of the efficacy of lysine supplementation to prevent or reduce the incidence of AD. Supplementation with adequate doses of lysine could prevent the development of AD.Keywords: lysine, herpes, Alzheimer’s dementia, HSV-1 Robert N RubeyDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2010, Iss Issue 1, Pp 707-710 (2010) |
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Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
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Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Robert N Rubey Could lysine supplementation prevent Alzheimer’s dementia? A novel hypothesis |
| description |
Robert N RubeyRetired, Red Lodge, Montana, USAAbstract: There is a growing body of evidence that implicates the herpes simplex type 1 virus (HSV-1) in the development of Alzheimer’s dementia (AD). HSV-1 has been found to be present in the cerebrum of the great majority of older adults, and in many of the same areas of the brain that are affected by AD. When active, the virus may contribute to the formation of the neurofibrillary tangles and amyloid plaques characteristic of AD. Like AD, HSV-1 encephalitis may cause long term memory loss. HSV-1 replication is suppressed in lysine-rich/arginine – poor environments, and population studies suggest that diets high in lysine and low in arginine may be associated with lower rates of AD. There are no prospective studies of the efficacy of lysine supplementation to prevent or reduce the incidence of AD. Supplementation with adequate doses of lysine could prevent the development of AD.Keywords: lysine, herpes, Alzheimer’s dementia, HSV-1 |
| format |
article |
| author |
Robert N Rubey |
| author_facet |
Robert N Rubey |
| author_sort |
Robert N Rubey |
| title |
Could lysine supplementation prevent Alzheimer’s dementia? A novel hypothesis |
| title_short |
Could lysine supplementation prevent Alzheimer’s dementia? A novel hypothesis |
| title_full |
Could lysine supplementation prevent Alzheimer’s dementia? A novel hypothesis |
| title_fullStr |
Could lysine supplementation prevent Alzheimer’s dementia? A novel hypothesis |
| title_full_unstemmed |
Could lysine supplementation prevent Alzheimer’s dementia? A novel hypothesis |
| title_sort |
could lysine supplementation prevent alzheimer’s dementia? a novel hypothesis |
| publisher |
Dove Medical Press |
| publishDate |
2010 |
| url |
https://doaj.org/article/c148f4d35b4848958bcd7e60a007ec43 |
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AT robertnrubey couldlysinesupplementationpreventalzheimeramprsquosdementiaanovelhypothesis |
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