Downregulation of serine protease HTRA1 is associated with poor survival in breast cancer.

HTRA1 is a highly conserved serine protease which has been implicated in suppression of epithelial-to-mesenchymal-transition (EMT) and cell motility in breast cancer. Its prognostic relevance for breast cancer is unclear so far. Therefore, we evaluated the impact of HTRA1 mRNA expression on patient...

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Autores principales: Anna Lehner, Viktor Magdolen, Tibor Schuster, Matthias Kotzsch, Marion Kiechle, Alfons Meindl, Fred C G J Sweep, Paul N Span, Eva Gross
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/c159e79a9b6943129bf471955d05f6aa
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