Disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy?

Functional microcirculatory abnormalities in the foot have been given much attention in the recent years for their potential pathogenetic role in thedevelopment of diabetic neuropathy and diabetic foot syndrome. This paper reviews data on the disturbances of skin microcirculation in lower extremitie...

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Autores principales:	Vadim Borisovich Bregovsky, I A Karpova, E S Alekseeva
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2011
Materias:	diabetes mellitus microangiopathy microcirculation polyneuropathy Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/c15df8df8cb24d5783b7ca419ae9512d
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spelling	oai:doaj.org-article:c15df8df8cb24d5783b7ca419ae9512d2021-11-14T09:00:16ZDisturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy?2072-03512072-037810.14341/2072-0351-6224https://doaj.org/article/c15df8df8cb24d5783b7ca419ae9512d2011-09-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6224https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Functional microcirculatory abnormalities in the foot have been given much attention in the recent years for their potential pathogenetic role in thedevelopment of diabetic neuropathy and diabetic foot syndrome. This paper reviews data on the disturbances of skin microcirculation in lower extremitieswith reference to the role of neuropathy and endothelial dysfunction in this pathology. Possible relationships between end-stage renal disease, highplantar pressure and compromised skin microcirculation are discussed. The influence of several drugs on foot skin microcirculation and prospects fortheir use for therapeutic purposes are considered.Vadim Borisovich BregovskyI A KarpovaE S AlekseevaEndocrinology Research Centrearticlediabetes mellitusmicroangiopathymicrocirculationpolyneuropathyNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 14, Iss 3, Pp 49-53 (2011)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	diabetes mellitus microangiopathy microcirculation polyneuropathy Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	diabetes mellitus microangiopathy microcirculation polyneuropathy Nutritional diseases. Deficiency diseases RC620-627 Vadim Borisovich Bregovsky I A Karpova E S Alekseeva Disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy?
description	Functional microcirculatory abnormalities in the foot have been given much attention in the recent years for their potential pathogenetic role in thedevelopment of diabetic neuropathy and diabetic foot syndrome. This paper reviews data on the disturbances of skin microcirculation in lower extremitieswith reference to the role of neuropathy and endothelial dysfunction in this pathology. Possible relationships between end-stage renal disease, highplantar pressure and compromised skin microcirculation are discussed. The influence of several drugs on foot skin microcirculation and prospects fortheir use for therapeutic purposes are considered.
format	article
author	Vadim Borisovich Bregovsky I A Karpova E S Alekseeva
author_facet	Vadim Borisovich Bregovsky I A Karpova E S Alekseeva
author_sort	Vadim Borisovich Bregovsky
title	Disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy?
title_short	Disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy?
title_full	Disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy?
title_fullStr	Disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy?
title_full_unstemmed	Disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy?
title_sort	disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy?
publisher	Endocrinology Research Centre
publishDate	2011
url	https://doaj.org/article/c15df8df8cb24d5783b7ca419ae9512d
work_keys_str_mv	AT vadimborisovichbregovsky disturbancesofskinmicrocirculationinlowerextremitiesindiabetesmellitusapathophysiologicalphenomenonoranobjectfortherapy AT iakarpova disturbancesofskinmicrocirculationinlowerextremitiesindiabetesmellitusapathophysiologicalphenomenonoranobjectfortherapy AT esalekseeva disturbancesofskinmicrocirculationinlowerextremitiesindiabetesmellitusapathophysiologicalphenomenonoranobjectfortherapy
_version_	1718429611286593536

Disturbances of skin microcirculation in lower extremities in diabetes mellitus:a pathophysiological phenomenon or an object for therapy?

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