SciBet as a portable and fast single cell type identifier

The increasing size of single cell sequencing data sets calls for scalable cell annotation methods. Here, the authors introduce SciBet, which uses a multinomial distribution model and maximum likelihood estimation for fast and accurate single cell identification.

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Auteurs principaux: Chenwei Li, Baolin Liu, Boxi Kang, Zedao Liu, Yedan Liu, Changya Chen, Xianwen Ren, Zemin Zhang
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/c160ac1e1a1e4a25b0baef251f5258dd
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Résumé:The increasing size of single cell sequencing data sets calls for scalable cell annotation methods. Here, the authors introduce SciBet, which uses a multinomial distribution model and maximum likelihood estimation for fast and accurate single cell identification.