SciBet as a portable and fast single cell type identifier

The increasing size of single cell sequencing data sets calls for scalable cell annotation methods. Here, the authors introduce SciBet, which uses a multinomial distribution model and maximum likelihood estimation for fast and accurate single cell identification.

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Detalles Bibliográficos
Autores principales: Chenwei Li, Baolin Liu, Boxi Kang, Zedao Liu, Yedan Liu, Changya Chen, Xianwen Ren, Zemin Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c160ac1e1a1e4a25b0baef251f5258dd
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Descripción
Sumario:The increasing size of single cell sequencing data sets calls for scalable cell annotation methods. Here, the authors introduce SciBet, which uses a multinomial distribution model and maximum likelihood estimation for fast and accurate single cell identification.