Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour

The suprachiasmatic nucleus (SCN) is the central regulator of circadian rhythms. Here the authors identify mouse Gpr176 as a pace modulator of this circadian clock and characterize its mode of action as coupling to Gz rather than Gi subunits.

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Autores principales:	Masao Doi, Iori Murai, Sumihiro Kunisue, Genzui Setsu, Naohiro Uchio, Rina Tanaka, Sakurako Kobayashi, Hiroyuki Shimatani, Hida Hayashi, Hsu-Wen Chao, Yuuki Nakagawa, Yukari Takahashi, Yunhong Hotta, Jun-ichirou Yasunaga, Masao Matsuoka, Michael H. Hastings, Hiroshi Kiyonari, Hitoshi Okamura
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c16b11b6441e475eb897bd5b32fd2eac
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spelling	oai:doaj.org-article:c16b11b6441e475eb897bd5b32fd2eac2021-12-02T17:31:48ZGpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour10.1038/ncomms105832041-1723https://doaj.org/article/c16b11b6441e475eb897bd5b32fd2eac2016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10583https://doaj.org/toc/2041-1723The suprachiasmatic nucleus (SCN) is the central regulator of circadian rhythms. Here the authors identify mouse Gpr176 as a pace modulator of this circadian clock and characterize its mode of action as coupling to Gz rather than Gi subunits.Masao DoiIori MuraiSumihiro KunisueGenzui SetsuNaohiro UchioRina TanakaSakurako KobayashiHiroyuki ShimataniHida HayashiHsu-Wen ChaoYuuki NakagawaYukari TakahashiYunhong HottaJun-ichirou YasunagaMasao MatsuokaMichael H. HastingsHiroshi KiyonariHitoshi OkamuraNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Masao Doi Iori Murai Sumihiro Kunisue Genzui Setsu Naohiro Uchio Rina Tanaka Sakurako Kobayashi Hiroyuki Shimatani Hida Hayashi Hsu-Wen Chao Yuuki Nakagawa Yukari Takahashi Yunhong Hotta Jun-ichirou Yasunaga Masao Matsuoka Michael H. Hastings Hiroshi Kiyonari Hitoshi Okamura Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour
description	The suprachiasmatic nucleus (SCN) is the central regulator of circadian rhythms. Here the authors identify mouse Gpr176 as a pace modulator of this circadian clock and characterize its mode of action as coupling to Gz rather than Gi subunits.
format	article
author	Masao Doi Iori Murai Sumihiro Kunisue Genzui Setsu Naohiro Uchio Rina Tanaka Sakurako Kobayashi Hiroyuki Shimatani Hida Hayashi Hsu-Wen Chao Yuuki Nakagawa Yukari Takahashi Yunhong Hotta Jun-ichirou Yasunaga Masao Matsuoka Michael H. Hastings Hiroshi Kiyonari Hitoshi Okamura
author_facet	Masao Doi Iori Murai Sumihiro Kunisue Genzui Setsu Naohiro Uchio Rina Tanaka Sakurako Kobayashi Hiroyuki Shimatani Hida Hayashi Hsu-Wen Chao Yuuki Nakagawa Yukari Takahashi Yunhong Hotta Jun-ichirou Yasunaga Masao Matsuoka Michael H. Hastings Hiroshi Kiyonari Hitoshi Okamura
author_sort	Masao Doi
title	Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour
title_short	Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour
title_full	Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour
title_fullStr	Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour
title_full_unstemmed	Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour
title_sort	gpr176 is a gz-linked orphan g-protein-coupled receptor that sets the pace of circadian behaviour
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/c16b11b6441e475eb897bd5b32fd2eac
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Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour

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