Genome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence

Brain volume and intelligence have been previously found to have shared genetic etiology, but the specific common genetic signals have not been identified. Here, the authors perform a genome-wide association study on brain volume, finding common genetic loci driving brain volume and intelligence.

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Autores principales: Philip R. Jansen, Mats Nagel, Kyoko Watanabe, Yongbin Wei, Jeanne E. Savage, Christiaan A. de Leeuw, Martijn P. van den Heuvel, Sophie van der Sluis, Danielle Posthuma
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c179006b77bc4e1cbdbd156edceda0f9
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spelling oai:doaj.org-article:c179006b77bc4e1cbdbd156edceda0f92021-12-02T14:41:25ZGenome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence10.1038/s41467-020-19378-52041-1723https://doaj.org/article/c179006b77bc4e1cbdbd156edceda0f92020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19378-5https://doaj.org/toc/2041-1723Brain volume and intelligence have been previously found to have shared genetic etiology, but the specific common genetic signals have not been identified. Here, the authors perform a genome-wide association study on brain volume, finding common genetic loci driving brain volume and intelligence.Philip R. JansenMats NagelKyoko WatanabeYongbin WeiJeanne E. SavageChristiaan A. de LeeuwMartijn P. van den HeuvelSophie van der SluisDanielle PosthumaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Philip R. Jansen
Mats Nagel
Kyoko Watanabe
Yongbin Wei
Jeanne E. Savage
Christiaan A. de Leeuw
Martijn P. van den Heuvel
Sophie van der Sluis
Danielle Posthuma
Genome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence
description Brain volume and intelligence have been previously found to have shared genetic etiology, but the specific common genetic signals have not been identified. Here, the authors perform a genome-wide association study on brain volume, finding common genetic loci driving brain volume and intelligence.
format article
author Philip R. Jansen
Mats Nagel
Kyoko Watanabe
Yongbin Wei
Jeanne E. Savage
Christiaan A. de Leeuw
Martijn P. van den Heuvel
Sophie van der Sluis
Danielle Posthuma
author_facet Philip R. Jansen
Mats Nagel
Kyoko Watanabe
Yongbin Wei
Jeanne E. Savage
Christiaan A. de Leeuw
Martijn P. van den Heuvel
Sophie van der Sluis
Danielle Posthuma
author_sort Philip R. Jansen
title Genome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence
title_short Genome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence
title_full Genome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence
title_fullStr Genome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence
title_full_unstemmed Genome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence
title_sort genome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/c179006b77bc4e1cbdbd156edceda0f9
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