Literature Overview of the IL-17 Inhibition from Psoriasis to COVID-19

Yulin Zou, Zudong Meng Department of Dermatology, Renmin Hospital, Hubei University of Medicine, Shiyan City, People’s Republic of ChinaCorrespondence: Zudong Meng Email zylmch1007@hbmu.edu.cnAbstract: The COVID-19 pandemic has posed a serious problem for drug anti-viral efficacy in combat...

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Main Authors:	Zou Y, Meng Z
Format:	article
Language:	EN
Published:	Dove Medical Press 2021
Subjects:	biologics covid-19 psoriasis therapy il-17 Pathology RB1-214 Therapeutics. Pharmacology RM1-950
Online Access:	https://doaj.org/article/c17d6b59e6564653a2e5d1bde94e5ef0
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spelling	oai:doaj.org-article:c17d6b59e6564653a2e5d1bde94e5ef02021-12-02T19:37:59ZLiterature Overview of the IL-17 Inhibition from Psoriasis to COVID-191178-7031https://doaj.org/article/c17d6b59e6564653a2e5d1bde94e5ef02021-11-01T00:00:00Zhttps://www.dovepress.com/literature-overview-of-the-il-17-inhibition-from-psoriasis-to-covid-19-peer-reviewed-fulltext-article-JIRhttps://doaj.org/toc/1178-7031Yulin Zou, Zudong Meng Department of Dermatology, Renmin Hospital, Hubei University of Medicine, Shiyan City, People’s Republic of ChinaCorrespondence: Zudong Meng Email zylmch1007@hbmu.edu.cnAbstract: The COVID-19 pandemic has posed a serious problem for drug anti-viral efficacy in combatting the cytokine storm triggered by SARS-CoV-2. From dermato-epidemiological studies conducted on psoriatic and other rheumatological patients, IL-17 inhibitors seem to attenuate or even prevent the cytokine storm and thus ICU referral. Furthermore, both in-vivo and in-vitro experiments suggest that IL-17 plays a key role in SARS-CoV-2 infection progression. Due to this evidence, we decided to summarize the literature findings on IL-17 inhibitors and COVID-19, maintaining psoriasis as the referral disease to better understand the extent of drug effects on the immune system.Keywords: biologics, COVID-19, psoriasis, therapy, IL-17Zou YMeng ZDove Medical Pressarticlebiologicscovid-19psoriasistherapyil-17PathologyRB1-214Therapeutics. PharmacologyRM1-950ENJournal of Inflammation Research, Vol Volume 14, Pp 5611-5618 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	biologics covid-19 psoriasis therapy il-17 Pathology RB1-214 Therapeutics. Pharmacology RM1-950
spellingShingle	biologics covid-19 psoriasis therapy il-17 Pathology RB1-214 Therapeutics. Pharmacology RM1-950 Zou Y Meng Z Literature Overview of the IL-17 Inhibition from Psoriasis to COVID-19
description	Yulin Zou, Zudong Meng Department of Dermatology, Renmin Hospital, Hubei University of Medicine, Shiyan City, People’s Republic of ChinaCorrespondence: Zudong Meng Email zylmch1007@hbmu.edu.cnAbstract: The COVID-19 pandemic has posed a serious problem for drug anti-viral efficacy in combatting the cytokine storm triggered by SARS-CoV-2. From dermato-epidemiological studies conducted on psoriatic and other rheumatological patients, IL-17 inhibitors seem to attenuate or even prevent the cytokine storm and thus ICU referral. Furthermore, both in-vivo and in-vitro experiments suggest that IL-17 plays a key role in SARS-CoV-2 infection progression. Due to this evidence, we decided to summarize the literature findings on IL-17 inhibitors and COVID-19, maintaining psoriasis as the referral disease to better understand the extent of drug effects on the immune system.Keywords: biologics, COVID-19, psoriasis, therapy, IL-17
format	article
author	Zou Y Meng Z
author_facet	Zou Y Meng Z
author_sort	Zou Y
title	Literature Overview of the IL-17 Inhibition from Psoriasis to COVID-19
title_short	Literature Overview of the IL-17 Inhibition from Psoriasis to COVID-19
title_full	Literature Overview of the IL-17 Inhibition from Psoriasis to COVID-19
title_fullStr	Literature Overview of the IL-17 Inhibition from Psoriasis to COVID-19
title_full_unstemmed	Literature Overview of the IL-17 Inhibition from Psoriasis to COVID-19
title_sort	literature overview of the il-17 inhibition from psoriasis to covid-19
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/c17d6b59e6564653a2e5d1bde94e5ef0
work_keys_str_mv	AT zouy literatureoverviewoftheil17inhibitionfrompsoriasistocovid19 AT mengz literatureoverviewoftheil17inhibitionfrompsoriasistocovid19
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Literature Overview of the IL-17 Inhibition from Psoriasis to COVID-19

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