The ubiquitin-like modifier FAT10 interferes with SUMO activation

FAT10 is an ubiquitin-like modifier that targets proteins to proteasomal degradation. Here, the authors show that FAT10 also regulates SUMO activation in vitro and in cells, providing evidence for functional crosstalk between two ubiquitin-like modifiers.

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Autores principales:	Annette Aichem, Carolin Sailer, Stella Ryu, Nicola Catone, Nicolas Stankovic-Valentin, Gunter Schmidtke, Frauke Melchior, Florian Stengel, Marcus Groettrup
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c189585808444a29aa898a977aa4e6e8
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spelling	oai:doaj.org-article:c189585808444a29aa898a977aa4e6e82021-12-02T15:35:58ZThe ubiquitin-like modifier FAT10 interferes with SUMO activation10.1038/s41467-019-12430-z2041-1723https://doaj.org/article/c189585808444a29aa898a977aa4e6e82019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12430-zhttps://doaj.org/toc/2041-1723FAT10 is an ubiquitin-like modifier that targets proteins to proteasomal degradation. Here, the authors show that FAT10 also regulates SUMO activation in vitro and in cells, providing evidence for functional crosstalk between two ubiquitin-like modifiers.Annette AichemCarolin SailerStella RyuNicola CatoneNicolas Stankovic-ValentinGunter SchmidtkeFrauke MelchiorFlorian StengelMarcus GroettrupNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Annette Aichem Carolin Sailer Stella Ryu Nicola Catone Nicolas Stankovic-Valentin Gunter Schmidtke Frauke Melchior Florian Stengel Marcus Groettrup The ubiquitin-like modifier FAT10 interferes with SUMO activation
description	FAT10 is an ubiquitin-like modifier that targets proteins to proteasomal degradation. Here, the authors show that FAT10 also regulates SUMO activation in vitro and in cells, providing evidence for functional crosstalk between two ubiquitin-like modifiers.
format	article
author	Annette Aichem Carolin Sailer Stella Ryu Nicola Catone Nicolas Stankovic-Valentin Gunter Schmidtke Frauke Melchior Florian Stengel Marcus Groettrup
author_facet	Annette Aichem Carolin Sailer Stella Ryu Nicola Catone Nicolas Stankovic-Valentin Gunter Schmidtke Frauke Melchior Florian Stengel Marcus Groettrup
author_sort	Annette Aichem
title	The ubiquitin-like modifier FAT10 interferes with SUMO activation
title_short	The ubiquitin-like modifier FAT10 interferes with SUMO activation
title_full	The ubiquitin-like modifier FAT10 interferes with SUMO activation
title_fullStr	The ubiquitin-like modifier FAT10 interferes with SUMO activation
title_full_unstemmed	The ubiquitin-like modifier FAT10 interferes with SUMO activation
title_sort	ubiquitin-like modifier fat10 interferes with sumo activation
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/c189585808444a29aa898a977aa4e6e8
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The ubiquitin-like modifier FAT10 interferes with SUMO activation

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