Synthesis of 14-Substituted-14H-Dibenzo[<i>a,j</i>]Xanthene Derivatives in Presence of Effective Synergetic Catalytic System Bleaching Earth Clay and PEG-600
The synthesis of 14-aryl 14H-dibenzo[<i>a,j</i>]xanthenes is achieved by a simple condensation reaction between β-naphthol with aryl or alkyl aldehydes in an effective synergetic catalytic system created by combining basic bleaching earth clay and PEG-600. The advantages of the present m...
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| Autores principales: | , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
MDPI AG
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/c189f48d6b9e4a1b9a4a8f30ae3864c8 |
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| Sumario: | The synthesis of 14-aryl 14H-dibenzo[<i>a,j</i>]xanthenes is achieved by a simple condensation reaction between β-naphthol with aryl or alkyl aldehydes in an effective synergetic catalytic system created by combining basic bleaching earth clay and PEG-600. The advantages of the present method include catalyst recyclability, superior product yield, a shorter reaction time and the avoidance of hazardous reagents. Synthesized xanthene derivatives were also screened for their antibacterial activity against <i>Staphylococcus aureus</i> (MTCC 96) and <i>Pseudomonas aeruginosa</i> (Wild). |
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