Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes

Aldosterone-producing zona glomerulosa cells in the adrenal gland arrange into rosette structures known to be important for morphogenesis. Here the authors show that the cells in the rosettes produce coordinated calcium activity bursts in response to angiotensin II that correlate with aldosterone pr...

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Autores principales:	Nick A. Guagliardo, Peter M. Klein, Christina A. Gancayco, Adam Lu, Sining Leng, Rany R. Makarem, Chelsea Cho, Craig G. Rusin, David T. Breault, Paula Q. Barrett, Mark P. Beenhakker
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c1975079f3f541bbb5287c6fb622c60d
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spelling	oai:doaj.org-article:c1975079f3f541bbb5287c6fb622c60d2021-12-02T17:31:10ZAngiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes10.1038/s41467-020-15408-42041-1723https://doaj.org/article/c1975079f3f541bbb5287c6fb622c60d2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15408-4https://doaj.org/toc/2041-1723Aldosterone-producing zona glomerulosa cells in the adrenal gland arrange into rosette structures known to be important for morphogenesis. Here the authors show that the cells in the rosettes produce coordinated calcium activity bursts in response to angiotensin II that correlate with aldosterone production level.Nick A. GuagliardoPeter M. KleinChristina A. GancaycoAdam LuSining LengRany R. MakaremChelsea ChoCraig G. RusinDavid T. BreaultPaula Q. BarrettMark P. BeenhakkerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nick A. Guagliardo Peter M. Klein Christina A. Gancayco Adam Lu Sining Leng Rany R. Makarem Chelsea Cho Craig G. Rusin David T. Breault Paula Q. Barrett Mark P. Beenhakker Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes
description	Aldosterone-producing zona glomerulosa cells in the adrenal gland arrange into rosette structures known to be important for morphogenesis. Here the authors show that the cells in the rosettes produce coordinated calcium activity bursts in response to angiotensin II that correlate with aldosterone production level.
format	article
author	Nick A. Guagliardo Peter M. Klein Christina A. Gancayco Adam Lu Sining Leng Rany R. Makarem Chelsea Cho Craig G. Rusin David T. Breault Paula Q. Barrett Mark P. Beenhakker
author_facet	Nick A. Guagliardo Peter M. Klein Christina A. Gancayco Adam Lu Sining Leng Rany R. Makarem Chelsea Cho Craig G. Rusin David T. Breault Paula Q. Barrett Mark P. Beenhakker
author_sort	Nick A. Guagliardo
title	Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes
title_short	Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes
title_full	Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes
title_fullStr	Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes
title_full_unstemmed	Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes
title_sort	angiotensin ii induces coordinated calcium bursts in aldosterone-producing adrenal rosettes
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/c1975079f3f541bbb5287c6fb622c60d
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Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes

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