Sudan ebolavirus long recovered survivors produce GP-specific Abs that are of the IgG1 subclass and preferentially bind FcγRI

Sudan ebolavirus long recovered survivors produce GP-specific Abs that are of the IgG1 subclass and preferentially bind FcγRI

Abstract Ebolavirus is a highly lethal pathogen, causing a severe hemorrhagic disease with a high fatality rate. To better understand immune correlates of protection by virus specific IgG, we investigated the evolution of the Fcγ receptors (FcγRs)-activating capabilities of antiviral IgG in serum sa...

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Autores principales: Olga Radinsky, Avishay Edri, Michael Brusilovsky, Shlomit Fedida-Metula, Ariel Sobarzo, Orly Gershoni-Yahalom, Julius Lutwama, John Dye, Leslie Lobel, Angel Porgador
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/c1a76fe3bf204533981c3fa5cf4aed1d
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