The Role of Nrf2 in Skeletal Muscle on Exercise Capacity

Nuclear factor erythroid 2-related factor 2 Nfe2l2 (Nrf2) is believed to play a crucial role in protecting cells against oxidative stress. In addition to its primary function of maintaining redox homeostasis, there is emerging evidence that Nrf2 is also involved in energy metabolism. In this review,...

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Autor principal:	Yu Kitaoka
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	Nrf2 oxidative stress skeletal muscle mitochondria Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/c1aa06ba869c4ed7a36734b394c12b0a
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spelling	oai:doaj.org-article:c1aa06ba869c4ed7a36734b394c12b0a2021-11-25T16:26:54ZThe Role of Nrf2 in Skeletal Muscle on Exercise Capacity10.3390/antiox101117122076-3921https://doaj.org/article/c1aa06ba869c4ed7a36734b394c12b0a2021-10-01T00:00:00Zhttps://www.mdpi.com/2076-3921/10/11/1712https://doaj.org/toc/2076-3921Nuclear factor erythroid 2-related factor 2 Nfe2l2 (Nrf2) is believed to play a crucial role in protecting cells against oxidative stress. In addition to its primary function of maintaining redox homeostasis, there is emerging evidence that Nrf2 is also involved in energy metabolism. In this review, we briefly discuss the role of Nrf2 in skeletal muscle metabolism from the perspective of exercise physiology. This article is part of a special issue “Mitochondrial Function, Reactive Oxygen/Nitrogen Species and Skeletal Muscle” edited by Håkan Westerblad and Takashi Yamada.Yu KitaokaMDPI AGarticleNrf2oxidative stressskeletal musclemitochondriaTherapeutics. PharmacologyRM1-950ENAntioxidants, Vol 10, Iss 1712, p 1712 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Nrf2 oxidative stress skeletal muscle mitochondria Therapeutics. Pharmacology RM1-950
spellingShingle	Nrf2 oxidative stress skeletal muscle mitochondria Therapeutics. Pharmacology RM1-950 Yu Kitaoka The Role of Nrf2 in Skeletal Muscle on Exercise Capacity
description	Nuclear factor erythroid 2-related factor 2 Nfe2l2 (Nrf2) is believed to play a crucial role in protecting cells against oxidative stress. In addition to its primary function of maintaining redox homeostasis, there is emerging evidence that Nrf2 is also involved in energy metabolism. In this review, we briefly discuss the role of Nrf2 in skeletal muscle metabolism from the perspective of exercise physiology. This article is part of a special issue “Mitochondrial Function, Reactive Oxygen/Nitrogen Species and Skeletal Muscle” edited by Håkan Westerblad and Takashi Yamada.
format	article
author	Yu Kitaoka
author_facet	Yu Kitaoka
author_sort	Yu Kitaoka
title	The Role of Nrf2 in Skeletal Muscle on Exercise Capacity
title_short	The Role of Nrf2 in Skeletal Muscle on Exercise Capacity
title_full	The Role of Nrf2 in Skeletal Muscle on Exercise Capacity
title_fullStr	The Role of Nrf2 in Skeletal Muscle on Exercise Capacity
title_full_unstemmed	The Role of Nrf2 in Skeletal Muscle on Exercise Capacity
title_sort	role of nrf2 in skeletal muscle on exercise capacity
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/c1aa06ba869c4ed7a36734b394c12b0a
work_keys_str_mv	AT yukitaoka theroleofnrf2inskeletalmuscleonexercisecapacity AT yukitaoka roleofnrf2inskeletalmuscleonexercisecapacity
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The Role of Nrf2 in Skeletal Muscle on Exercise Capacity

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