Intravenous treatment of choroidal neovascularization by photo-targeted nanoparticles

Current treatments of wet age-related macular degeneration require repeated injections of active drugs into the vitreous. Here Wang et al. develop nanoparticles that when injected intravenously can be targeted to the eye by irradiation with blue light, allowing local and enhanced drug release in the...

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Autores principales:	Yanfei Wang, Chi-Hsiu Liu, Tianjiao Ji, Manisha Mehta, Weiping Wang, Elizabeth Marino, Jing Chen, Daniel S. Kohane
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c1aa796c9d924c3f95e0266f537c4573
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spelling	oai:doaj.org-article:c1aa796c9d924c3f95e0266f537c45732021-12-02T16:57:20ZIntravenous treatment of choroidal neovascularization by photo-targeted nanoparticles10.1038/s41467-019-08690-42041-1723https://doaj.org/article/c1aa796c9d924c3f95e0266f537c45732019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08690-4https://doaj.org/toc/2041-1723Current treatments of wet age-related macular degeneration require repeated injections of active drugs into the vitreous. Here Wang et al. develop nanoparticles that when injected intravenously can be targeted to the eye by irradiation with blue light, allowing local and enhanced drug release in the back of the eye, and providing an alternative to current delivery strategies.Yanfei WangChi-Hsiu LiuTianjiao JiManisha MehtaWeiping WangElizabeth MarinoJing ChenDaniel S. KohaneNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yanfei Wang Chi-Hsiu Liu Tianjiao Ji Manisha Mehta Weiping Wang Elizabeth Marino Jing Chen Daniel S. Kohane Intravenous treatment of choroidal neovascularization by photo-targeted nanoparticles
description	Current treatments of wet age-related macular degeneration require repeated injections of active drugs into the vitreous. Here Wang et al. develop nanoparticles that when injected intravenously can be targeted to the eye by irradiation with blue light, allowing local and enhanced drug release in the back of the eye, and providing an alternative to current delivery strategies.
format	article
author	Yanfei Wang Chi-Hsiu Liu Tianjiao Ji Manisha Mehta Weiping Wang Elizabeth Marino Jing Chen Daniel S. Kohane
author_facet	Yanfei Wang Chi-Hsiu Liu Tianjiao Ji Manisha Mehta Weiping Wang Elizabeth Marino Jing Chen Daniel S. Kohane
author_sort	Yanfei Wang
title	Intravenous treatment of choroidal neovascularization by photo-targeted nanoparticles
title_short	Intravenous treatment of choroidal neovascularization by photo-targeted nanoparticles
title_full	Intravenous treatment of choroidal neovascularization by photo-targeted nanoparticles
title_fullStr	Intravenous treatment of choroidal neovascularization by photo-targeted nanoparticles
title_full_unstemmed	Intravenous treatment of choroidal neovascularization by photo-targeted nanoparticles
title_sort	intravenous treatment of choroidal neovascularization by photo-targeted nanoparticles
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/c1aa796c9d924c3f95e0266f537c4573
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Intravenous treatment of choroidal neovascularization by photo-targeted nanoparticles

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