Prognostic value of health-related quality of life in elderly patients hospitalized with heart failure

Predrag Erceg,1,2 Nebojsa Despotovic,1,2 Dragoslav P Milosevic,1,2 Ivan Soldatovic,1 Gordana Mihajlovic,1,2 Vladan Vukcevic,1,3 Predrag Mitrovic,1,3 Natasa Markovic-Nikolic,1,4 Milica Micovic,2 Dragica Mitrovic,5 Mladen Davidovic11Faculty of Medicine, University of Belgrade, Belgrade, Serbia; 2Clini...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Erceg P, Despotovic N, Milosevic DP, Soldatovic I, Mihajlovic G, Vukcevic V, Mitrovic P, Markovic-Nikolic N, Micovic M, Mitrovic D, Davidovic M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	aged heart disease self-perception of health prognosis Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/c1ab5d5cae74436fa4dcf0def8857920
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c1ab5d5cae74436fa4dcf0def8857920
record_format	dspace
spelling	oai:doaj.org-article:c1ab5d5cae74436fa4dcf0def88579202021-12-02T05:40:04ZPrognostic value of health-related quality of life in elderly patients hospitalized with heart failure1178-1998https://doaj.org/article/c1ab5d5cae74436fa4dcf0def88579202019-05-01T00:00:00Zhttps://www.dovepress.com/prognostic-value-of-health-related-quality-of-life-in-elderly-patients-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Predrag Erceg,1,2 Nebojsa Despotovic,1,2 Dragoslav P Milosevic,1,2 Ivan Soldatovic,1 Gordana Mihajlovic,1,2 Vladan Vukcevic,1,3 Predrag Mitrovic,1,3 Natasa Markovic-Nikolic,1,4 Milica Micovic,2 Dragica Mitrovic,5 Mladen Davidovic11Faculty of Medicine, University of Belgrade, Belgrade, Serbia; 2Clinical Department of Geriatrics, “Zvezdara” University Hospital, Belgrade, Serbia; 3Cardiology Clinic, Clinical Center of Serbia, Belgrade, Serbia; 4Clinical Department of Cardiology, “Zvezdara” University Hospital, Belgrade, Serbia; 5Department of Physical Medicine and Rehabilitation, “Zvezdara” University Hospital, Belgrade, SerbiaPurpose: Previous research has shown that poor health-related quality of life (HRQOL) is associated with adverse long-term prognosis in patients with heart failure (HF); however, there have been inconsistencies among studies and not all of them confirmed the prognostic value of HRQOL. In addition, few studies involved elderly patients and most focused on all-cause mortality and HF-related hospitalization as outcomes. The aim of our study was to determine whether HRQOL is a predictor and an independent predictor of long-term cardiac mortality, all-cause mortality, and HF-related rehospitalization in elderly patients hospitalized with HF.Patients and methods: This prospective observational study included 200 elderly patients hospitalized with HF in Serbia. HRQOL was measured using the Minnesota Living with Heart Failure questionnaire (MLHFQ). The median follow-up period was 28 months. The primary outcome was cardiac mortality, and all-cause mortality and HF-related rehospitalization were secondary outcomes. Survival analysis was conducted using the Kaplan–Meier method and Cox-proportional hazards regression.Results: Subjects with poor HRQOL (higher than the median MLHFQ score) had a higher probability of cardiac mortality (P=0.029) and HF-related rehospitalization (P=0.001) during long-term follow-up. Poor HRQOL was an independent predictor of cardiac mortality (HR: 2.051, 95% CI: 1.260–3.339, P=0.004), all-cause mortality (HR: 1.620, 95% CI: 1.076–2.438, P=0.021), and HF-related rehospitalization (HR: 2.040, 95% CI: 1.290–3.227, P=0.002).Conclusion: HRQOL is an independent predictor of long-term cardiac mortality in elderly patients hospitalized with HF. It also independently predicts all-cause mortality and HF-related rehospitalization. HRQOL could be used as a complementary clinical predictive tool in this patient population.Keywords: aged, heart disease, self-perception of health, prognosisErceg PDespotovic NMilosevic DPSoldatovic IMihajlovic GVukcevic VMitrovic PMarkovic-Nikolic NMicovic MMitrovic DDavidovic MDove Medical Pressarticleagedheart diseaseself-perception of healthprognosisGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 14, Pp 935-945 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	aged heart disease self-perception of health prognosis Geriatrics RC952-954.6
spellingShingle	aged heart disease self-perception of health prognosis Geriatrics RC952-954.6 Erceg P Despotovic N Milosevic DP Soldatovic I Mihajlovic G Vukcevic V Mitrovic P Markovic-Nikolic N Micovic M Mitrovic D Davidovic M Prognostic value of health-related quality of life in elderly patients hospitalized with heart failure
description	Predrag Erceg,1,2 Nebojsa Despotovic,1,2 Dragoslav P Milosevic,1,2 Ivan Soldatovic,1 Gordana Mihajlovic,1,2 Vladan Vukcevic,1,3 Predrag Mitrovic,1,3 Natasa Markovic-Nikolic,1,4 Milica Micovic,2 Dragica Mitrovic,5 Mladen Davidovic11Faculty of Medicine, University of Belgrade, Belgrade, Serbia; 2Clinical Department of Geriatrics, “Zvezdara” University Hospital, Belgrade, Serbia; 3Cardiology Clinic, Clinical Center of Serbia, Belgrade, Serbia; 4Clinical Department of Cardiology, “Zvezdara” University Hospital, Belgrade, Serbia; 5Department of Physical Medicine and Rehabilitation, “Zvezdara” University Hospital, Belgrade, SerbiaPurpose: Previous research has shown that poor health-related quality of life (HRQOL) is associated with adverse long-term prognosis in patients with heart failure (HF); however, there have been inconsistencies among studies and not all of them confirmed the prognostic value of HRQOL. In addition, few studies involved elderly patients and most focused on all-cause mortality and HF-related hospitalization as outcomes. The aim of our study was to determine whether HRQOL is a predictor and an independent predictor of long-term cardiac mortality, all-cause mortality, and HF-related rehospitalization in elderly patients hospitalized with HF.Patients and methods: This prospective observational study included 200 elderly patients hospitalized with HF in Serbia. HRQOL was measured using the Minnesota Living with Heart Failure questionnaire (MLHFQ). The median follow-up period was 28 months. The primary outcome was cardiac mortality, and all-cause mortality and HF-related rehospitalization were secondary outcomes. Survival analysis was conducted using the Kaplan–Meier method and Cox-proportional hazards regression.Results: Subjects with poor HRQOL (higher than the median MLHFQ score) had a higher probability of cardiac mortality (P=0.029) and HF-related rehospitalization (P=0.001) during long-term follow-up. Poor HRQOL was an independent predictor of cardiac mortality (HR: 2.051, 95% CI: 1.260–3.339, P=0.004), all-cause mortality (HR: 1.620, 95% CI: 1.076–2.438, P=0.021), and HF-related rehospitalization (HR: 2.040, 95% CI: 1.290–3.227, P=0.002).Conclusion: HRQOL is an independent predictor of long-term cardiac mortality in elderly patients hospitalized with HF. It also independently predicts all-cause mortality and HF-related rehospitalization. HRQOL could be used as a complementary clinical predictive tool in this patient population.Keywords: aged, heart disease, self-perception of health, prognosis
format	article
author	Erceg P Despotovic N Milosevic DP Soldatovic I Mihajlovic G Vukcevic V Mitrovic P Markovic-Nikolic N Micovic M Mitrovic D Davidovic M
author_facet	Erceg P Despotovic N Milosevic DP Soldatovic I Mihajlovic G Vukcevic V Mitrovic P Markovic-Nikolic N Micovic M Mitrovic D Davidovic M
author_sort	Erceg P
title	Prognostic value of health-related quality of life in elderly patients hospitalized with heart failure
title_short	Prognostic value of health-related quality of life in elderly patients hospitalized with heart failure
title_full	Prognostic value of health-related quality of life in elderly patients hospitalized with heart failure
title_fullStr	Prognostic value of health-related quality of life in elderly patients hospitalized with heart failure
title_full_unstemmed	Prognostic value of health-related quality of life in elderly patients hospitalized with heart failure
title_sort	prognostic value of health-related quality of life in elderly patients hospitalized with heart failure
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/c1ab5d5cae74436fa4dcf0def8857920
work_keys_str_mv	AT ercegp prognosticvalueofhealthrelatedqualityoflifeinelderlypatientshospitalizedwithheartfailure AT despotovicn prognosticvalueofhealthrelatedqualityoflifeinelderlypatientshospitalizedwithheartfailure AT milosevicdp prognosticvalueofhealthrelatedqualityoflifeinelderlypatientshospitalizedwithheartfailure AT soldatovici prognosticvalueofhealthrelatedqualityoflifeinelderlypatientshospitalizedwithheartfailure AT mihajlovicg prognosticvalueofhealthrelatedqualityoflifeinelderlypatientshospitalizedwithheartfailure AT vukcevicv prognosticvalueofhealthrelatedqualityoflifeinelderlypatientshospitalizedwithheartfailure AT mitrovicp prognosticvalueofhealthrelatedqualityoflifeinelderlypatientshospitalizedwithheartfailure AT markovicnikolicn prognosticvalueofhealthrelatedqualityoflifeinelderlypatientshospitalizedwithheartfailure AT micovicm prognosticvalueofhealthrelatedqualityoflifeinelderlypatientshospitalizedwithheartfailure AT mitrovicd prognosticvalueofhealthrelatedqualityoflifeinelderlypatientshospitalizedwithheartfailure AT davidovicm prognosticvalueofhealthrelatedqualityoflifeinelderlypatientshospitalizedwithheartfailure
_version_	1718400319914770432

Prognostic value of health-related quality of life in elderly patients hospitalized with heart failure

Ejemplares similares