Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration

Lymphotoxin regulates lymphoid organ architecture and adhesion molecules involved in lymphocyte trafficking. Here the authors show that lymphotoxin produced by regulatory T cells promotes their migration to the draining lymph nodes by engaging its cognate receptor on lymphatic endothelial cells.

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Autores principales: C. Colin Brinkman, Daiki Iwami, Molly K. Hritzo, Yanbao Xiong, Sarwat Ahmad, Thomas Simon, Keli L. Hippen, Bruce R. Blazar, Jonathan S. Bromberg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/c1b7c04c5e344820ad62ca3e16a0863c
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spelling oai:doaj.org-article:c1b7c04c5e344820ad62ca3e16a0863c2021-12-02T16:49:42ZTreg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration10.1038/ncomms120212041-1723https://doaj.org/article/c1b7c04c5e344820ad62ca3e16a0863c2016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms12021https://doaj.org/toc/2041-1723Lymphotoxin regulates lymphoid organ architecture and adhesion molecules involved in lymphocyte trafficking. Here the authors show that lymphotoxin produced by regulatory T cells promotes their migration to the draining lymph nodes by engaging its cognate receptor on lymphatic endothelial cells.C. Colin BrinkmanDaiki IwamiMolly K. HritzoYanbao XiongSarwat AhmadThomas SimonKeli L. HippenBruce R. BlazarJonathan S. BrombergNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
C. Colin Brinkman
Daiki Iwami
Molly K. Hritzo
Yanbao Xiong
Sarwat Ahmad
Thomas Simon
Keli L. Hippen
Bruce R. Blazar
Jonathan S. Bromberg
Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration
description Lymphotoxin regulates lymphoid organ architecture and adhesion molecules involved in lymphocyte trafficking. Here the authors show that lymphotoxin produced by regulatory T cells promotes their migration to the draining lymph nodes by engaging its cognate receptor on lymphatic endothelial cells.
format article
author C. Colin Brinkman
Daiki Iwami
Molly K. Hritzo
Yanbao Xiong
Sarwat Ahmad
Thomas Simon
Keli L. Hippen
Bruce R. Blazar
Jonathan S. Bromberg
author_facet C. Colin Brinkman
Daiki Iwami
Molly K. Hritzo
Yanbao Xiong
Sarwat Ahmad
Thomas Simon
Keli L. Hippen
Bruce R. Blazar
Jonathan S. Bromberg
author_sort C. Colin Brinkman
title Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration
title_short Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration
title_full Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration
title_fullStr Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration
title_full_unstemmed Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration
title_sort treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/c1b7c04c5e344820ad62ca3e16a0863c
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