Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration
Lymphotoxin regulates lymphoid organ architecture and adhesion molecules involved in lymphocyte trafficking. Here the authors show that lymphotoxin produced by regulatory T cells promotes their migration to the draining lymph nodes by engaging its cognate receptor on lymphatic endothelial cells.
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Nature Portfolio
2016
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oai:doaj.org-article:c1b7c04c5e344820ad62ca3e16a0863c2021-12-02T16:49:42ZTreg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration10.1038/ncomms120212041-1723https://doaj.org/article/c1b7c04c5e344820ad62ca3e16a0863c2016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms12021https://doaj.org/toc/2041-1723Lymphotoxin regulates lymphoid organ architecture and adhesion molecules involved in lymphocyte trafficking. Here the authors show that lymphotoxin produced by regulatory T cells promotes their migration to the draining lymph nodes by engaging its cognate receptor on lymphatic endothelial cells.C. Colin BrinkmanDaiki IwamiMolly K. HritzoYanbao XiongSarwat AhmadThomas SimonKeli L. HippenBruce R. BlazarJonathan S. BrombergNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016) |
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Science Q |
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Science Q C. Colin Brinkman Daiki Iwami Molly K. Hritzo Yanbao Xiong Sarwat Ahmad Thomas Simon Keli L. Hippen Bruce R. Blazar Jonathan S. Bromberg Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration |
description |
Lymphotoxin regulates lymphoid organ architecture and adhesion molecules involved in lymphocyte trafficking. Here the authors show that lymphotoxin produced by regulatory T cells promotes their migration to the draining lymph nodes by engaging its cognate receptor on lymphatic endothelial cells. |
format |
article |
author |
C. Colin Brinkman Daiki Iwami Molly K. Hritzo Yanbao Xiong Sarwat Ahmad Thomas Simon Keli L. Hippen Bruce R. Blazar Jonathan S. Bromberg |
author_facet |
C. Colin Brinkman Daiki Iwami Molly K. Hritzo Yanbao Xiong Sarwat Ahmad Thomas Simon Keli L. Hippen Bruce R. Blazar Jonathan S. Bromberg |
author_sort |
C. Colin Brinkman |
title |
Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration |
title_short |
Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration |
title_full |
Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration |
title_fullStr |
Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration |
title_full_unstemmed |
Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration |
title_sort |
treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/c1b7c04c5e344820ad62ca3e16a0863c |
work_keys_str_mv |
AT ccolinbrinkman tregengagelymphotoxinbetareceptorforafferentlymphatictransendothelialmigration AT daikiiwami tregengagelymphotoxinbetareceptorforafferentlymphatictransendothelialmigration AT mollykhritzo tregengagelymphotoxinbetareceptorforafferentlymphatictransendothelialmigration AT yanbaoxiong tregengagelymphotoxinbetareceptorforafferentlymphatictransendothelialmigration AT sarwatahmad tregengagelymphotoxinbetareceptorforafferentlymphatictransendothelialmigration AT thomassimon tregengagelymphotoxinbetareceptorforafferentlymphatictransendothelialmigration AT kelilhippen tregengagelymphotoxinbetareceptorforafferentlymphatictransendothelialmigration AT brucerblazar tregengagelymphotoxinbetareceptorforafferentlymphatictransendothelialmigration AT jonathansbromberg tregengagelymphotoxinbetareceptorforafferentlymphatictransendothelialmigration |
_version_ |
1718383238116802560 |