ACTH and PMX53 recover synaptic transcriptome alterations in a rat model of infantile spasms

Abstract We profiled the gene expression in the hypothalamic arcuate nuclei (ARC) of 20 male and 20 female rats to determine the infantile spasms (IS) related transcriptomic alteration of neurotransmission and recovery following two treatments. Rats were prenatally exposed to betamethasone or saline...

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Autores principales: Dumitru A. Iacobaş, Tamar Chachua, Sanda Iacobaş, Melissa J. Benson, Karin Borges, Jana Velíšková, Libor Velíšek
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c1c038ab3d384dc3a8d178380bb0ec24
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