ACTH and PMX53 recover synaptic transcriptome alterations in a rat model of infantile spasms
Abstract We profiled the gene expression in the hypothalamic arcuate nuclei (ARC) of 20 male and 20 female rats to determine the infantile spasms (IS) related transcriptomic alteration of neurotransmission and recovery following two treatments. Rats were prenatally exposed to betamethasone or saline...
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Main Authors: | Dumitru A. Iacobaş, Tamar Chachua, Sanda Iacobaş, Melissa J. Benson, Karin Borges, Jana Velíšková, Libor Velíšek |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Online Access: | https://doaj.org/article/c1c038ab3d384dc3a8d178380bb0ec24 |
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