ACTH and PMX53 recover synaptic transcriptome alterations in a rat model of infantile spasms

Abstract We profiled the gene expression in the hypothalamic arcuate nuclei (ARC) of 20 male and 20 female rats to determine the infantile spasms (IS) related transcriptomic alteration of neurotransmission and recovery following two treatments. Rats were prenatally exposed to betamethasone or saline...

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Bibliographic Details
Main Authors: Dumitru A. Iacobaş, Tamar Chachua, Sanda Iacobaş, Melissa J. Benson, Karin Borges, Jana Velíšková, Libor Velíšek
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
R
Q
Online Access:https://doaj.org/article/c1c038ab3d384dc3a8d178380bb0ec24
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