PATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIES

Abstract. We have studied some features of immune system in children with common episodes of acute respiratory infections accompanied by lymphadenopathies (LAP). Among this cohort of the patients, a decrease in general immune reactions was revealed, accomplished by polyclonal activation of distinct...

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Autores principales:	N. N. Popov, A. N. Savvo, E. A. Romanova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	т-lymphocytes в-lymphocytes lymphocyte subpopulations immunity lymphadenopathies children Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/c1dfbb5e084b4059a1eab26f0c778c35
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spelling	oai:doaj.org-article:c1dfbb5e084b4059a1eab26f0c778c352021-11-18T08:03:40ZPATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIES1563-06252313-741X10.15789/1563-0625-2009-6-581-586https://doaj.org/article/c1dfbb5e084b4059a1eab26f0c778c352014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/374https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. We have studied some features of immune system in children with common episodes of acute respiratory infections accompanied by lymphadenopathies (LAP). Among this cohort of the patients, a decrease in general immune reactions was revealed, accomplished by polyclonal activation of distinct lymphocyte subpopulations. Certain immune changes have been discerned in children with common infections accompanied by a LAP syndrome, such as an increased ratios of T- and B-lymphocytes carrying CD69 and CD25 activation molecules, a CD71 marker typical for proliferating cells, NKT-cells positive for CD3, CD56, CD8 with high cytokine-producing potential, as well as increased rates of spontaneous blast transformation of lymphocytes, both in course of the disease, and following recovery of the children.N. N. PopovA. N. SavvoE. A. RomanovaSPb RAACIarticleт-lymphocytesв-lymphocyteslymphocyte subpopulationsimmunitylymphadenopathieschildrenImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 11, Iss 6, Pp 581-586 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	т-lymphocytes в-lymphocytes lymphocyte subpopulations immunity lymphadenopathies children Immunologic diseases. Allergy RC581-607
spellingShingle	т-lymphocytes в-lymphocytes lymphocyte subpopulations immunity lymphadenopathies children Immunologic diseases. Allergy RC581-607 N. N. Popov A. N. Savvo E. A. Romanova PATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIES
description	Abstract. We have studied some features of immune system in children with common episodes of acute respiratory infections accompanied by lymphadenopathies (LAP). Among this cohort of the patients, a decrease in general immune reactions was revealed, accomplished by polyclonal activation of distinct lymphocyte subpopulations. Certain immune changes have been discerned in children with common infections accompanied by a LAP syndrome, such as an increased ratios of T- and B-lymphocytes carrying CD69 and CD25 activation molecules, a CD71 marker typical for proliferating cells, NKT-cells positive for CD3, CD56, CD8 with high cytokine-producing potential, as well as increased rates of spontaneous blast transformation of lymphocytes, both in course of the disease, and following recovery of the children.
format	article
author	N. N. Popov A. N. Savvo E. A. Romanova
author_facet	N. N. Popov A. N. Savvo E. A. Romanova
author_sort	N. N. Popov
title	PATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIES
title_short	PATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIES
title_full	PATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIES
title_fullStr	PATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIES
title_full_unstemmed	PATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIES
title_sort	patterns of local and general immunity among children suffering from common illnesses accomplished by lymphadenopathies
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/c1dfbb5e084b4059a1eab26f0c778c35
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_version_	1718422505995108352

PATTERNS OF LOCAL AND GENERAL IMMUNITY AMONG CHILDREN SUFFERING FROM COMMON ILLNESSES ACCOMPLISHED BY LYMPHADENOPATHIES

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