Deacylated tRNA Accumulation Is a Trigger for Bacterial Antibiotic Persistence Independent of the Stringent Response
Bacterial antibiotic persistence is a transient physiological state wherein cells become dormant and thereby evade being killed by antibiotics. Once the antibiotic is removed, bacterial persisters are able to resuscitate and repopulate.
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American Society for Microbiology
2021
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oai:doaj.org-article:c1ef9d2b186d43299520d29a1d1b62e92021-11-03T21:15:04ZDeacylated tRNA Accumulation Is a Trigger for Bacterial Antibiotic Persistence Independent of the Stringent Response2150-751110.1128/mBio.01132-21https://doaj.org/article/c1ef9d2b186d43299520d29a1d1b62e92021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01132-21https://doaj.org/toc/2150-7511 Bacterial antibiotic persistence is a transient physiological state wherein cells become dormant and thereby evade being killed by antibiotics. Once the antibiotic is removed, bacterial persisters are able to resuscitate and repopulate.Whitney N. WoodKyle MohlerJesse RinehartMichael IbbaAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 3 (2021) |
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Microbiology QR1-502 |
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Microbiology QR1-502 Whitney N. Wood Kyle Mohler Jesse Rinehart Michael Ibba Deacylated tRNA Accumulation Is a Trigger for Bacterial Antibiotic Persistence Independent of the Stringent Response |
description |
Bacterial antibiotic persistence is a transient physiological state wherein cells become dormant and thereby evade being killed by antibiotics. Once the antibiotic is removed, bacterial persisters are able to resuscitate and repopulate. |
format |
article |
author |
Whitney N. Wood Kyle Mohler Jesse Rinehart Michael Ibba |
author_facet |
Whitney N. Wood Kyle Mohler Jesse Rinehart Michael Ibba |
author_sort |
Whitney N. Wood |
title |
Deacylated tRNA Accumulation Is a Trigger for Bacterial Antibiotic Persistence Independent of the Stringent Response |
title_short |
Deacylated tRNA Accumulation Is a Trigger for Bacterial Antibiotic Persistence Independent of the Stringent Response |
title_full |
Deacylated tRNA Accumulation Is a Trigger for Bacterial Antibiotic Persistence Independent of the Stringent Response |
title_fullStr |
Deacylated tRNA Accumulation Is a Trigger for Bacterial Antibiotic Persistence Independent of the Stringent Response |
title_full_unstemmed |
Deacylated tRNA Accumulation Is a Trigger for Bacterial Antibiotic Persistence Independent of the Stringent Response |
title_sort |
deacylated trna accumulation is a trigger for bacterial antibiotic persistence independent of the stringent response |
publisher |
American Society for Microbiology |
publishDate |
2021 |
url |
https://doaj.org/article/c1ef9d2b186d43299520d29a1d1b62e9 |
work_keys_str_mv |
AT whitneynwood deacylatedtrnaaccumulationisatriggerforbacterialantibioticpersistenceindependentofthestringentresponse AT kylemohler deacylatedtrnaaccumulationisatriggerforbacterialantibioticpersistenceindependentofthestringentresponse AT jesserinehart deacylatedtrnaaccumulationisatriggerforbacterialantibioticpersistenceindependentofthestringentresponse AT michaelibba deacylatedtrnaaccumulationisatriggerforbacterialantibioticpersistenceindependentofthestringentresponse |
_version_ |
1718445420101763072 |