Nuclear membrane protein Lem2 regulates nuclear size through membrane flow

Nuclear size scales with cell size, but the underlying mechanisms are unclear. Here, the authors report in fission yeast that the inner nuclear membrane protein Lem2 and the ER membrane protein Lnp1 are barriers to membrane flow and propose that they maintain nuclear size in proportion to cell membr...

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Autores principales: Kazunori Kume, Helena Cantwell, Alana Burrell, Paul Nurse
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/c1f90115a3bc463dbe14573025028420
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