CDYL suppresses epileptogenesis in mice through repression of axonal Nav1.6 sodium channel expression

CDYL suppresses epileptogenesis in mice through repression of axonal Nav1.6 sodium channel expression

Alterations in intrinsic plasticity are important in epilepsy. Here the authors show that the epigenetic factor CDYL regulates the gene expression of the voltage gated sodium channel, Nav1.6, which contributes to seizures in a rat model of epilepsy.

Guardado en:
Detalles Bibliográficos
Autores principales: Yongqing Liu, Shirong Lai, Weining Ma, Wei Ke, Chan Zhang, Shumeng Liu, Yu Zhang, Fei Pei, Shaoyi Li, Ming Yi, Yousheng Shu, Yongfeng Shang, Jing Liang, Zhuo Huang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/c1fec91be8b04fc981937dd1ca6abdea
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares