Chromatin conformation analysis of primary patient tissue using a low input Hi-C method

Chromatin conformation studies are limited by the large amounts of starting material required to perform current protocols. Here the authors present Low-C, a Hi-C method for low amounts of input material and produce Low-C maps from primary B-cells of a diffuse large B-cell lymphoma patient, demonstr...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Noelia Díaz, Kai Kruse, Tabea Erdmann, Annette M. Staiger, German Ott, Georg Lenz, Juan M. Vaquerizas
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c203c0b2003646cea3a7eb3e347a72fc
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c203c0b2003646cea3a7eb3e347a72fc
record_format	dspace
spelling	oai:doaj.org-article:c203c0b2003646cea3a7eb3e347a72fc2021-12-02T17:31:17ZChromatin conformation analysis of primary patient tissue using a low input Hi-C method10.1038/s41467-018-06961-02041-1723https://doaj.org/article/c203c0b2003646cea3a7eb3e347a72fc2018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06961-0https://doaj.org/toc/2041-1723Chromatin conformation studies are limited by the large amounts of starting material required to perform current protocols. Here the authors present Low-C, a Hi-C method for low amounts of input material and produce Low-C maps from primary B-cells of a diffuse large B-cell lymphoma patient, demonstrating the suitability of Low-C to analyse rare cell populations.Noelia DíazKai KruseTabea ErdmannAnnette M. StaigerGerman OttGeorg LenzJuan M. VaquerizasNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Noelia Díaz Kai Kruse Tabea Erdmann Annette M. Staiger German Ott Georg Lenz Juan M. Vaquerizas Chromatin conformation analysis of primary patient tissue using a low input Hi-C method
description	Chromatin conformation studies are limited by the large amounts of starting material required to perform current protocols. Here the authors present Low-C, a Hi-C method for low amounts of input material and produce Low-C maps from primary B-cells of a diffuse large B-cell lymphoma patient, demonstrating the suitability of Low-C to analyse rare cell populations.
format	article
author	Noelia Díaz Kai Kruse Tabea Erdmann Annette M. Staiger German Ott Georg Lenz Juan M. Vaquerizas
author_facet	Noelia Díaz Kai Kruse Tabea Erdmann Annette M. Staiger German Ott Georg Lenz Juan M. Vaquerizas
author_sort	Noelia Díaz
title	Chromatin conformation analysis of primary patient tissue using a low input Hi-C method
title_short	Chromatin conformation analysis of primary patient tissue using a low input Hi-C method
title_full	Chromatin conformation analysis of primary patient tissue using a low input Hi-C method
title_fullStr	Chromatin conformation analysis of primary patient tissue using a low input Hi-C method
title_full_unstemmed	Chromatin conformation analysis of primary patient tissue using a low input Hi-C method
title_sort	chromatin conformation analysis of primary patient tissue using a low input hi-c method
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/c203c0b2003646cea3a7eb3e347a72fc
work_keys_str_mv	AT noeliadiaz chromatinconformationanalysisofprimarypatienttissueusingalowinputhicmethod AT kaikruse chromatinconformationanalysisofprimarypatienttissueusingalowinputhicmethod AT tabeaerdmann chromatinconformationanalysisofprimarypatienttissueusingalowinputhicmethod AT annettemstaiger chromatinconformationanalysisofprimarypatienttissueusingalowinputhicmethod AT germanott chromatinconformationanalysisofprimarypatienttissueusingalowinputhicmethod AT georglenz chromatinconformationanalysisofprimarypatienttissueusingalowinputhicmethod AT juanmvaquerizas chromatinconformationanalysisofprimarypatienttissueusingalowinputhicmethod
_version_	1718380698313687040

Chromatin conformation analysis of primary patient tissue using a low input Hi-C method

Ejemplares similares