Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines

Due to poor specificity, the current pharmacotherapy of atherosclerosis has limited therapeutic efficacy. Here, the authors show that a macrophage-biomimetic nanomedicine effectively alleviates atherosclerosis via targeted pharmacotherapy and sequestration of proinflammatory cytokines and chemokines...

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Autores principales:	Cheng Gao, Qiaoxian Huang, Conghui Liu, Cheryl H. T. Kwong, Ludan Yue, Jian-Bo Wan, Simon M. Y. Lee, Ruibing Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c2130094bf8f43128180c567fdb490e3
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spelling	oai:doaj.org-article:c2130094bf8f43128180c567fdb490e32021-12-02T15:49:52ZTreatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines10.1038/s41467-020-16439-72041-1723https://doaj.org/article/c2130094bf8f43128180c567fdb490e32020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16439-7https://doaj.org/toc/2041-1723Due to poor specificity, the current pharmacotherapy of atherosclerosis has limited therapeutic efficacy. Here, the authors show that a macrophage-biomimetic nanomedicine effectively alleviates atherosclerosis via targeted pharmacotherapy and sequestration of proinflammatory cytokines and chemokines.Cheng GaoQiaoxian HuangConghui LiuCheryl H. T. KwongLudan YueJian-Bo WanSimon M. Y. LeeRuibing WangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Cheng Gao Qiaoxian Huang Conghui Liu Cheryl H. T. Kwong Ludan Yue Jian-Bo Wan Simon M. Y. Lee Ruibing Wang Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines
description	Due to poor specificity, the current pharmacotherapy of atherosclerosis has limited therapeutic efficacy. Here, the authors show that a macrophage-biomimetic nanomedicine effectively alleviates atherosclerosis via targeted pharmacotherapy and sequestration of proinflammatory cytokines and chemokines.
format	article
author	Cheng Gao Qiaoxian Huang Conghui Liu Cheryl H. T. Kwong Ludan Yue Jian-Bo Wan Simon M. Y. Lee Ruibing Wang
author_facet	Cheng Gao Qiaoxian Huang Conghui Liu Cheryl H. T. Kwong Ludan Yue Jian-Bo Wan Simon M. Y. Lee Ruibing Wang
author_sort	Cheng Gao
title	Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines
title_short	Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines
title_full	Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines
title_fullStr	Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines
title_full_unstemmed	Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines
title_sort	treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/c2130094bf8f43128180c567fdb490e3
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Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines

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