The structure of a β2-microglobulin fibril suggests a molecular basis for its amyloid polymorphism
Impaired kidney function can lead to an increase of β2-microglobulin (β2m) serum levels, which can cause β2m aggregation and amyloid fibril formation. Here the authors combine cryo-EM and magic angle spinning NMR measurements to determine the structure of a β2m fibril and they also present the low r...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2018
|
| Subjects: | |
| Online Access: | https://doaj.org/article/c2131f4762074ff88b7f948f11bb5fd7 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|