Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments

Butyrophilin-like genes are emerging as central to tissue associated γδ T cell compartments. Here, the authors show that the butyropilin-like gene-products exert their effects as combinatorially diverse heteromers that differentially affect the selection and maintenance of skin-resident and gut-resi...

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Autores principales: Anett Jandke, Daisy Melandri, Leticia Monin, Dmitry S. Ushakov, Adam G. Laing, Pierre Vantourout, Philip East, Takeshi Nitta, Tomoya Narita, Hiroshi Takayanagi, Regina Feederle, Adrian Hayday
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Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c213401a85c342bf9b8247f63d992ad0
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spelling oai:doaj.org-article:c213401a85c342bf9b8247f63d992ad02021-12-02T18:46:58ZButyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments10.1038/s41467-020-17557-y2041-1723https://doaj.org/article/c213401a85c342bf9b8247f63d992ad02020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17557-yhttps://doaj.org/toc/2041-1723Butyrophilin-like genes are emerging as central to tissue associated γδ T cell compartments. Here, the authors show that the butyropilin-like gene-products exert their effects as combinatorially diverse heteromers that differentially affect the selection and maintenance of skin-resident and gut-resident intraepithelial γδ T-cell populations.Anett JandkeDaisy MelandriLeticia MoninDmitry S. UshakovAdam G. LaingPierre VantouroutPhilip EastTakeshi NittaTomoya NaritaHiroshi TakayanagiRegina FeederleAdrian HaydayNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Anett Jandke
Daisy Melandri
Leticia Monin
Dmitry S. Ushakov
Adam G. Laing
Pierre Vantourout
Philip East
Takeshi Nitta
Tomoya Narita
Hiroshi Takayanagi
Regina Feederle
Adrian Hayday
Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments
description Butyrophilin-like genes are emerging as central to tissue associated γδ T cell compartments. Here, the authors show that the butyropilin-like gene-products exert their effects as combinatorially diverse heteromers that differentially affect the selection and maintenance of skin-resident and gut-resident intraepithelial γδ T-cell populations.
format article
author Anett Jandke
Daisy Melandri
Leticia Monin
Dmitry S. Ushakov
Adam G. Laing
Pierre Vantourout
Philip East
Takeshi Nitta
Tomoya Narita
Hiroshi Takayanagi
Regina Feederle
Adrian Hayday
author_facet Anett Jandke
Daisy Melandri
Leticia Monin
Dmitry S. Ushakov
Adam G. Laing
Pierre Vantourout
Philip East
Takeshi Nitta
Tomoya Narita
Hiroshi Takayanagi
Regina Feederle
Adrian Hayday
author_sort Anett Jandke
title Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments
title_short Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments
title_full Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments
title_fullStr Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments
title_full_unstemmed Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments
title_sort butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ t cell compartments
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/c213401a85c342bf9b8247f63d992ad0
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