Identification of ASCL1 as a determinant for human iPSC-derived dopaminergic neurons
Abstract During cellular specification, transcription factors orchestrate cellular decisions through gene regulation. By hijacking these transcriptional networks, human pluripotent stem cells (hPSCs) can be specialized into neurons with different molecular identities for the purposes of regenerative...
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Main Authors: | Aaron M. Earley, Lena F. Burbulla, Dimitri Krainc, Rajeshwar Awatramani |
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Format: | article |
Language: | EN |
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Nature Portfolio
2021
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Online Access: | https://doaj.org/article/c21875a492da40c9b0c929e0d4c3f82a |
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