Identification of ASCL1 as a determinant for human iPSC-derived dopaminergic neurons

Abstract During cellular specification, transcription factors orchestrate cellular decisions through gene regulation. By hijacking these transcriptional networks, human pluripotent stem cells (hPSCs) can be specialized into neurons with different molecular identities for the purposes of regenerative...

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Bibliographic Details
Main Authors: Aaron M. Earley, Lena F. Burbulla, Dimitri Krainc, Rajeshwar Awatramani
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/c21875a492da40c9b0c929e0d4c3f82a
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