Identification of ASCL1 as a determinant for human iPSC-derived dopaminergic neurons

Abstract During cellular specification, transcription factors orchestrate cellular decisions through gene regulation. By hijacking these transcriptional networks, human pluripotent stem cells (hPSCs) can be specialized into neurons with different molecular identities for the purposes of regenerative...

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Auteurs principaux: Aaron M. Earley, Lena F. Burbulla, Dimitri Krainc, Rajeshwar Awatramani
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/c21875a492da40c9b0c929e0d4c3f82a
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