Multimodal two-photon imaging using a second harmonic generation-specific dye

Current dyes for second harmonic generation (SHG) imaging strongly fluoresce, limiting their application. Here the authors develop a SHG-specific dye, Ap3, that partitions into cell membranes, displays sensitivity to membrane potential and has virtually no fluorescence emission at SHG imaging wavele...

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Autores principales: Mutsuo Nuriya, Shun Fukushima, Atsuya Momotake, Takanori Shinotsuka, Masato Yasui, Tatsuo Arai
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/c2224404c31b4790835e965a4aff82da
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spelling oai:doaj.org-article:c2224404c31b4790835e965a4aff82da2021-12-02T17:32:51ZMultimodal two-photon imaging using a second harmonic generation-specific dye10.1038/ncomms115572041-1723https://doaj.org/article/c2224404c31b4790835e965a4aff82da2016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11557https://doaj.org/toc/2041-1723Current dyes for second harmonic generation (SHG) imaging strongly fluoresce, limiting their application. Here the authors develop a SHG-specific dye, Ap3, that partitions into cell membranes, displays sensitivity to membrane potential and has virtually no fluorescence emission at SHG imaging wavelengths.Mutsuo NuriyaShun FukushimaAtsuya MomotakeTakanori ShinotsukaMasato YasuiTatsuo AraiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Mutsuo Nuriya
Shun Fukushima
Atsuya Momotake
Takanori Shinotsuka
Masato Yasui
Tatsuo Arai
Multimodal two-photon imaging using a second harmonic generation-specific dye
description Current dyes for second harmonic generation (SHG) imaging strongly fluoresce, limiting their application. Here the authors develop a SHG-specific dye, Ap3, that partitions into cell membranes, displays sensitivity to membrane potential and has virtually no fluorescence emission at SHG imaging wavelengths.
format article
author Mutsuo Nuriya
Shun Fukushima
Atsuya Momotake
Takanori Shinotsuka
Masato Yasui
Tatsuo Arai
author_facet Mutsuo Nuriya
Shun Fukushima
Atsuya Momotake
Takanori Shinotsuka
Masato Yasui
Tatsuo Arai
author_sort Mutsuo Nuriya
title Multimodal two-photon imaging using a second harmonic generation-specific dye
title_short Multimodal two-photon imaging using a second harmonic generation-specific dye
title_full Multimodal two-photon imaging using a second harmonic generation-specific dye
title_fullStr Multimodal two-photon imaging using a second harmonic generation-specific dye
title_full_unstemmed Multimodal two-photon imaging using a second harmonic generation-specific dye
title_sort multimodal two-photon imaging using a second harmonic generation-specific dye
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/c2224404c31b4790835e965a4aff82da
work_keys_str_mv AT mutsuonuriya multimodaltwophotonimagingusingasecondharmonicgenerationspecificdye
AT shunfukushima multimodaltwophotonimagingusingasecondharmonicgenerationspecificdye
AT atsuyamomotake multimodaltwophotonimagingusingasecondharmonicgenerationspecificdye
AT takanorishinotsuka multimodaltwophotonimagingusingasecondharmonicgenerationspecificdye
AT masatoyasui multimodaltwophotonimagingusingasecondharmonicgenerationspecificdye
AT tatsuoarai multimodaltwophotonimagingusingasecondharmonicgenerationspecificdye
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