Bone marrow stromal cells from MDS and AML patients show increased adipogenic potential with reduced Delta-like-1 expression

Bone marrow stromal cells from MDS and AML patients show increased adipogenic potential with reduced Delta-like-1 expression

Abstract Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are clonal hematopoietic stem cell disorders with a poor prognosis, especially for elderly patients. Increasing evidence suggests that alterations in the non-hematopoietic microenvironment (bone marrow niche) can contribute to...

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Autores principales: Marie-Theresa Weickert, Judith S. Hecker, Michèle C. Buck, Christina Schreck, Jennifer Rivière, Matthias Schiemann, Katharina Schallmoser, Florian Bassermann, Dirk Strunk, Robert A. J. Oostendorp, Katharina S. Götze
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/c226cd0ba70e465cbd553e5471ceb2e7
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