IMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIA

Abstract. Thirty-seven children (7 to 14 years old) with chronic inflammatory lung diseases (ILD) were under study. It was revealed that the contents of T-lymphocytes with CD3+ and CD4+ markers, and B-lymphocytes (CD20+) were relatively decreased in the patients, but their absolute amounts proved to...

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Autores principales:	B. I. Kuznik, B. Ts. Batozghargalova, Yu. A. Vitkovsky
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	inflammatory lung diseases immunity lymphocyte-platelet adhesion Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/c22bf0afadbc4aefaa0e5aba622b92fe
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spelling	oai:doaj.org-article:c22bf0afadbc4aefaa0e5aba622b92fe2021-11-18T08:03:39ZIMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIA1563-06252313-741X10.15789/1563-0625-2008-6-583-588https://doaj.org/article/c22bf0afadbc4aefaa0e5aba622b92fe2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/273https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Thirty-seven children (7 to 14 years old) with chronic inflammatory lung diseases (ILD) were under study. It was revealed that the contents of T-lymphocytes with CD3+ and CD4+ markers, and B-lymphocytes (CD20+) were relatively decreased in the patients, but their absolute amounts proved to be increased, along with sufficiently decreased CD4+/CD8+ ratio, and diminished IgA, IgG and IgM concentrations. The numbers of lymphocyte able to adhere to platelets was relatively decreased, being, however, increased in absolute counts. In the patients with ILD, we have found increased levels of IL-1β, IL-8, TNFα, IFNα, IFNγ. The lymphocyte-to-platelet adherence is an objective test that reflects functional state of cell immunity. (Med. Immunol., vol. 10, N 6, pp 583-588).B. I. KuznikB. Ts. BatozghargalovaYu. A. VitkovskySPb RAACIarticleinflammatory lung diseasesimmunitylymphocyte-platelet adhesionImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 10, Iss 6, Pp 583-588 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	inflammatory lung diseases immunity lymphocyte-platelet adhesion Immunologic diseases. Allergy RC581-607
spellingShingle	inflammatory lung diseases immunity lymphocyte-platelet adhesion Immunologic diseases. Allergy RC581-607 B. I. Kuznik B. Ts. Batozghargalova Yu. A. Vitkovsky IMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIA
description	Abstract. Thirty-seven children (7 to 14 years old) with chronic inflammatory lung diseases (ILD) were under study. It was revealed that the contents of T-lymphocytes with CD3+ and CD4+ markers, and B-lymphocytes (CD20+) were relatively decreased in the patients, but their absolute amounts proved to be increased, along with sufficiently decreased CD4+/CD8+ ratio, and diminished IgA, IgG and IgM concentrations. The numbers of lymphocyte able to adhere to platelets was relatively decreased, being, however, increased in absolute counts. In the patients with ILD, we have found increased levels of IL-1β, IL-8, TNFα, IFNα, IFNγ. The lymphocyte-to-platelet adherence is an objective test that reflects functional state of cell immunity. (Med. Immunol., vol. 10, N 6, pp 583-588).
format	article
author	B. I. Kuznik B. Ts. Batozghargalova Yu. A. Vitkovsky
author_facet	B. I. Kuznik B. Ts. Batozghargalova Yu. A. Vitkovsky
author_sort	B. I. Kuznik
title	IMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIA
title_short	IMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIA
title_full	IMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIA
title_fullStr	IMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIA
title_full_unstemmed	IMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIA
title_sort	immune state and lymphocyte-to-platelet adhesion in children with chronic deforming bronchitis and bronchiectasia
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/c22bf0afadbc4aefaa0e5aba622b92fe
work_keys_str_mv	AT bikuznik immunestateandlymphocytetoplateletadhesioninchildrenwithchronicdeformingbronchitisandbronchiectasia AT btsbatozghargalova immunestateandlymphocytetoplateletadhesioninchildrenwithchronicdeformingbronchitisandbronchiectasia AT yuavitkovsky immunestateandlymphocytetoplateletadhesioninchildrenwithchronicdeformingbronchitisandbronchiectasia
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IMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIA

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