Particle slip velocity influences inertial focusing of particles in curved microchannels

Abstract Size based separation and identification of particles in microfluidics through purely hydrodynamic means has gained significant interest due to a number of possible biomedical applications. Curved micro-channels, particularly spiral micro-channels with rectangular cross-section and the dyna...

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Autores principales: Saurabh Deshpande, Phanindra Tallapragada
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c2395822b527419db60ebc23ff30f416
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spelling oai:doaj.org-article:c2395822b527419db60ebc23ff30f4162021-12-02T15:08:18ZParticle slip velocity influences inertial focusing of particles in curved microchannels10.1038/s41598-018-30171-92045-2322https://doaj.org/article/c2395822b527419db60ebc23ff30f4162018-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-30171-9https://doaj.org/toc/2045-2322Abstract Size based separation and identification of particles in microfluidics through purely hydrodynamic means has gained significant interest due to a number of possible biomedical applications. Curved micro-channels, particularly spiral micro-channels with rectangular cross-section and the dynamics of particles in such channels have been extensively researched to achieve size based separation of particles. In this paper we present evidence that sheds new light on the dynamics of particles in such curved channels; that a unique particle slip velocity is associated with the focusing positions in the cross sections, which leads to a balance of forces. Our experiments therefore imply that the forces acting on the particle lead to convergence to an attractor in both the physical space (the cross section of the channel) and the slip velocity space.Saurabh DeshpandePhanindra TallapragadaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Saurabh Deshpande
Phanindra Tallapragada
Particle slip velocity influences inertial focusing of particles in curved microchannels
description Abstract Size based separation and identification of particles in microfluidics through purely hydrodynamic means has gained significant interest due to a number of possible biomedical applications. Curved micro-channels, particularly spiral micro-channels with rectangular cross-section and the dynamics of particles in such channels have been extensively researched to achieve size based separation of particles. In this paper we present evidence that sheds new light on the dynamics of particles in such curved channels; that a unique particle slip velocity is associated with the focusing positions in the cross sections, which leads to a balance of forces. Our experiments therefore imply that the forces acting on the particle lead to convergence to an attractor in both the physical space (the cross section of the channel) and the slip velocity space.
format article
author Saurabh Deshpande
Phanindra Tallapragada
author_facet Saurabh Deshpande
Phanindra Tallapragada
author_sort Saurabh Deshpande
title Particle slip velocity influences inertial focusing of particles in curved microchannels
title_short Particle slip velocity influences inertial focusing of particles in curved microchannels
title_full Particle slip velocity influences inertial focusing of particles in curved microchannels
title_fullStr Particle slip velocity influences inertial focusing of particles in curved microchannels
title_full_unstemmed Particle slip velocity influences inertial focusing of particles in curved microchannels
title_sort particle slip velocity influences inertial focusing of particles in curved microchannels
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/c2395822b527419db60ebc23ff30f416
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