Find and cut-and-transfer (FiCAT) mammalian genome engineering

Mammalian genome engineering has advanced tremendously over the last decade, however there is still a need for robust gene writing with size scaling capacity. Here the authors present Find Cut-and-Transfer (FiCAT) technology to delivery large targeted payload insertion in cell lines and in vivo in m...

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Autores principales:	Maria Pallarès-Masmitjà, Dimitrije Ivančić, Júlia Mir-Pedrol, Jessica Jaraba-Wallace, Tommaso Tagliani, Baldomero Oliva, Amal Rahmeh, Avencia Sánchez-Mejías, Marc Güell
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c23e566832b248cfab7f31975632a946
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spelling	oai:doaj.org-article:c23e566832b248cfab7f31975632a9462021-12-05T12:22:17ZFind and cut-and-transfer (FiCAT) mammalian genome engineering10.1038/s41467-021-27183-x2041-1723https://doaj.org/article/c23e566832b248cfab7f31975632a9462021-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27183-xhttps://doaj.org/toc/2041-1723Mammalian genome engineering has advanced tremendously over the last decade, however there is still a need for robust gene writing with size scaling capacity. Here the authors present Find Cut-and-Transfer (FiCAT) technology to delivery large targeted payload insertion in cell lines and in vivo in mouse models.Maria Pallarès-MasmitjàDimitrije IvančićJúlia Mir-PedrolJessica Jaraba-WallaceTommaso TaglianiBaldomero OlivaAmal RahmehAvencia Sánchez-MejíasMarc GüellNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Maria Pallarès-Masmitjà Dimitrije Ivančić Júlia Mir-Pedrol Jessica Jaraba-Wallace Tommaso Tagliani Baldomero Oliva Amal Rahmeh Avencia Sánchez-Mejías Marc Güell Find and cut-and-transfer (FiCAT) mammalian genome engineering
description	Mammalian genome engineering has advanced tremendously over the last decade, however there is still a need for robust gene writing with size scaling capacity. Here the authors present Find Cut-and-Transfer (FiCAT) technology to delivery large targeted payload insertion in cell lines and in vivo in mouse models.
format	article
author	Maria Pallarès-Masmitjà Dimitrije Ivančić Júlia Mir-Pedrol Jessica Jaraba-Wallace Tommaso Tagliani Baldomero Oliva Amal Rahmeh Avencia Sánchez-Mejías Marc Güell
author_facet	Maria Pallarès-Masmitjà Dimitrije Ivančić Júlia Mir-Pedrol Jessica Jaraba-Wallace Tommaso Tagliani Baldomero Oliva Amal Rahmeh Avencia Sánchez-Mejías Marc Güell
author_sort	Maria Pallarès-Masmitjà
title	Find and cut-and-transfer (FiCAT) mammalian genome engineering
title_short	Find and cut-and-transfer (FiCAT) mammalian genome engineering
title_full	Find and cut-and-transfer (FiCAT) mammalian genome engineering
title_fullStr	Find and cut-and-transfer (FiCAT) mammalian genome engineering
title_full_unstemmed	Find and cut-and-transfer (FiCAT) mammalian genome engineering
title_sort	find and cut-and-transfer (ficat) mammalian genome engineering
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c23e566832b248cfab7f31975632a946
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Find and cut-and-transfer (FiCAT) mammalian genome engineering

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