Polygoni Multiflori Radix Praeparata Ethanol Extract Exerts a Protective Effect Against High-Fat Diet Induced Non-Alcoholic Fatty Liver Disease in Mice by Remodeling Intestinal Microbial Structure and Maintaining Metabolic Homeostasis of Bile Acids

Polygoni Multiflori Radix Praeparata Ethanol Extract Exerts a Protective Effect Against High-Fat Diet Induced Non-Alcoholic Fatty Liver Disease in Mice by Remodeling Intestinal Microbial Structure and Maintaining Metabolic Homeostasis of Bile Acids

In the prescription of Traditional Chinese Medicine for lipid metabolism, Polygoni Multiflori Radix Preparata (ZhiHeShouWu, RPMP) was widely used. In recent years, RPMP ethanol extract has been reported for the treatment of non-alcoholic fatty liver disease (NAFLD). However, the role of RPMP ethanol...

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Bibliographic Details
Main Authors: Xuyang Dai, Linfeng He, Naihua Hu, Chaocheng Guo, Mengting Zhou, Xingtao Zhao, Cheng Wang, Lihong Gong, Cheng Ma, Xinyan Xue, Yunxia Li
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
NAFLD
high-fat diet
intestinal barrier
intestinal microbial
bile acids
Therapeutics. Pharmacology
RM1-950
Online Access:https://doaj.org/article/c23f68796ac641b9ad4a8ed99ec30e0d
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