Proteomic characterization of acyclovir-induced nephrotoxicity in a mouse model.

Acyclovir (ACV) is an effective and widely used antiviral agent. However, its clinical application is limited by severe nephrotoxicity. We assessed ACV-induced nephrotoxicity and identified the differentially expressed proteins using mass spectrometry-based proteomic analysis. In total, 30 ICR mice...

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Autores principales: Hong Lu, Ya-Juan Han, Jia-Dong Xu, Wen-Min Xing, Jie Chen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/c245c241f1e7413f85a6bfc521bbea2e
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