Paracrine Regulation of Alveolar Epithelial Damage and Repair Responses by Human Lung-Resident Mesenchymal Stromal Cells

Paracrine Regulation of Alveolar Epithelial Damage and Repair Responses by Human Lung-Resident Mesenchymal Stromal Cells

COPD is characterized by irreversible lung tissue damage. We hypothesized that lung-derived mesenchymal stromal cells (LMSCs) reduce alveolar epithelial damage via paracrine processes, and may thus be suitable for cell-based strategies in COPD. We aimed to assess whether COPD-derived LMSCs display a...

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Bibliographic Details
Main Authors: Dennis M. L. W. Kruk, Marissa Wisman, Jacobien A. Noordhoek, Mehmet Nizamoglu, Marnix R. Jonker, Harold G. de Bruin, Karla Arevalo Gomez, Nick H. T. ten Hacken, Simon D. Pouwels, Irene H. Heijink
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
COPD
emphysema
cell therapy
lung repair
MSCs
alveolar epithelium
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/c260538f10634f8fb47eb09a8a7cee22
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https://doaj.org/article/c260538f10634f8fb47eb09a8a7cee22

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