Balancing a genetic toggle switch by real-time feedback control and periodic forcing

Cybergenetics aims to monitor and regulate cellular processes in real-time using computer monitoring and feedback of biological readouts. Here the authors use a feedback loop and periodic forcing to maintain cells with a bistable synthetic circuit near its unstable state.

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Autores principales: Jean-Baptiste Lugagne, Sebastián Sosa Carrillo, Melanie Kirch, Agnes Köhler, Gregory Batt, Pascal Hersen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c27529a75daa46a5bb91afbce34bb1dc
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spelling oai:doaj.org-article:c27529a75daa46a5bb91afbce34bb1dc2021-12-02T14:41:10ZBalancing a genetic toggle switch by real-time feedback control and periodic forcing10.1038/s41467-017-01498-02041-1723https://doaj.org/article/c27529a75daa46a5bb91afbce34bb1dc2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01498-0https://doaj.org/toc/2041-1723Cybergenetics aims to monitor and regulate cellular processes in real-time using computer monitoring and feedback of biological readouts. Here the authors use a feedback loop and periodic forcing to maintain cells with a bistable synthetic circuit near its unstable state.Jean-Baptiste LugagneSebastián Sosa CarrilloMelanie KirchAgnes KöhlerGregory BattPascal HersenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jean-Baptiste Lugagne
Sebastián Sosa Carrillo
Melanie Kirch
Agnes Köhler
Gregory Batt
Pascal Hersen
Balancing a genetic toggle switch by real-time feedback control and periodic forcing
description Cybergenetics aims to monitor and regulate cellular processes in real-time using computer monitoring and feedback of biological readouts. Here the authors use a feedback loop and periodic forcing to maintain cells with a bistable synthetic circuit near its unstable state.
format article
author Jean-Baptiste Lugagne
Sebastián Sosa Carrillo
Melanie Kirch
Agnes Köhler
Gregory Batt
Pascal Hersen
author_facet Jean-Baptiste Lugagne
Sebastián Sosa Carrillo
Melanie Kirch
Agnes Köhler
Gregory Batt
Pascal Hersen
author_sort Jean-Baptiste Lugagne
title Balancing a genetic toggle switch by real-time feedback control and periodic forcing
title_short Balancing a genetic toggle switch by real-time feedback control and periodic forcing
title_full Balancing a genetic toggle switch by real-time feedback control and periodic forcing
title_fullStr Balancing a genetic toggle switch by real-time feedback control and periodic forcing
title_full_unstemmed Balancing a genetic toggle switch by real-time feedback control and periodic forcing
title_sort balancing a genetic toggle switch by real-time feedback control and periodic forcing
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/c27529a75daa46a5bb91afbce34bb1dc
work_keys_str_mv AT jeanbaptistelugagne balancingagenetictoggleswitchbyrealtimefeedbackcontrolandperiodicforcing
AT sebastiansosacarrillo balancingagenetictoggleswitchbyrealtimefeedbackcontrolandperiodicforcing
AT melaniekirch balancingagenetictoggleswitchbyrealtimefeedbackcontrolandperiodicforcing
AT agneskohler balancingagenetictoggleswitchbyrealtimefeedbackcontrolandperiodicforcing
AT gregorybatt balancingagenetictoggleswitchbyrealtimefeedbackcontrolandperiodicforcing
AT pascalhersen balancingagenetictoggleswitchbyrealtimefeedbackcontrolandperiodicforcing
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