Balancing a genetic toggle switch by real-time feedback control and periodic forcing
Cybergenetics aims to monitor and regulate cellular processes in real-time using computer monitoring and feedback of biological readouts. Here the authors use a feedback loop and periodic forcing to maintain cells with a bistable synthetic circuit near its unstable state.
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Nature Portfolio
2017
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oai:doaj.org-article:c27529a75daa46a5bb91afbce34bb1dc2021-12-02T14:41:10ZBalancing a genetic toggle switch by real-time feedback control and periodic forcing10.1038/s41467-017-01498-02041-1723https://doaj.org/article/c27529a75daa46a5bb91afbce34bb1dc2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01498-0https://doaj.org/toc/2041-1723Cybergenetics aims to monitor and regulate cellular processes in real-time using computer monitoring and feedback of biological readouts. Here the authors use a feedback loop and periodic forcing to maintain cells with a bistable synthetic circuit near its unstable state.Jean-Baptiste LugagneSebastián Sosa CarrilloMelanie KirchAgnes KöhlerGregory BattPascal HersenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017) |
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Science Q Jean-Baptiste Lugagne Sebastián Sosa Carrillo Melanie Kirch Agnes Köhler Gregory Batt Pascal Hersen Balancing a genetic toggle switch by real-time feedback control and periodic forcing |
description |
Cybergenetics aims to monitor and regulate cellular processes in real-time using computer monitoring and feedback of biological readouts. Here the authors use a feedback loop and periodic forcing to maintain cells with a bistable synthetic circuit near its unstable state. |
format |
article |
author |
Jean-Baptiste Lugagne Sebastián Sosa Carrillo Melanie Kirch Agnes Köhler Gregory Batt Pascal Hersen |
author_facet |
Jean-Baptiste Lugagne Sebastián Sosa Carrillo Melanie Kirch Agnes Köhler Gregory Batt Pascal Hersen |
author_sort |
Jean-Baptiste Lugagne |
title |
Balancing a genetic toggle switch by real-time feedback control and periodic forcing |
title_short |
Balancing a genetic toggle switch by real-time feedback control and periodic forcing |
title_full |
Balancing a genetic toggle switch by real-time feedback control and periodic forcing |
title_fullStr |
Balancing a genetic toggle switch by real-time feedback control and periodic forcing |
title_full_unstemmed |
Balancing a genetic toggle switch by real-time feedback control and periodic forcing |
title_sort |
balancing a genetic toggle switch by real-time feedback control and periodic forcing |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/c27529a75daa46a5bb91afbce34bb1dc |
work_keys_str_mv |
AT jeanbaptistelugagne balancingagenetictoggleswitchbyrealtimefeedbackcontrolandperiodicforcing AT sebastiansosacarrillo balancingagenetictoggleswitchbyrealtimefeedbackcontrolandperiodicforcing AT melaniekirch balancingagenetictoggleswitchbyrealtimefeedbackcontrolandperiodicforcing AT agneskohler balancingagenetictoggleswitchbyrealtimefeedbackcontrolandperiodicforcing AT gregorybatt balancingagenetictoggleswitchbyrealtimefeedbackcontrolandperiodicforcing AT pascalhersen balancingagenetictoggleswitchbyrealtimefeedbackcontrolandperiodicforcing |
_version_ |
1718390017285423104 |