Transplantation of discarded livers following viability testing with normothermic machine perfusion

The shortage of viable donated livers limits patient access to liver transplantation. Here the authors report the use of normothermic machine perfusion to help identify viable organs from livers discarded based on current clinical criteria, which are then transplanted to recipients in a single-arm c...

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Autores principales: Hynek Mergental, Richard W. Laing, Amanda J. Kirkham, M. Thamara P. R. Perera, Yuri L. Boteon, Joseph Attard, Darren Barton, Stuart Curbishley, Manpreet Wilkhu, Desley A. H. Neil, Stefan G. Hübscher, Paolo Muiesan, John R. Isaac, Keith J. Roberts, Manuel Abradelo, Andrea Schlegel, James Ferguson, Hentie Cilliers, Julian Bion, David H. Adams, Chris Morris, Peter J. Friend, Christina Yap, Simon C. Afford, Darius F. Mirza
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Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c280eba6b1264d549b001554a3c7ab18
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spelling oai:doaj.org-article:c280eba6b1264d549b001554a3c7ab182021-12-02T17:40:33ZTransplantation of discarded livers following viability testing with normothermic machine perfusion10.1038/s41467-020-16251-32041-1723https://doaj.org/article/c280eba6b1264d549b001554a3c7ab182020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16251-3https://doaj.org/toc/2041-1723The shortage of viable donated livers limits patient access to liver transplantation. Here the authors report the use of normothermic machine perfusion to help identify viable organs from livers discarded based on current clinical criteria, which are then transplanted to recipients in a single-arm clinical trial.Hynek MergentalRichard W. LaingAmanda J. KirkhamM. Thamara P. R. PereraYuri L. BoteonJoseph AttardDarren BartonStuart CurbishleyManpreet WilkhuDesley A. H. NeilStefan G. HübscherPaolo MuiesanJohn R. IsaacKeith J. RobertsManuel AbradeloAndrea SchlegelJames FergusonHentie CilliersJulian BionDavid H. AdamsChris MorrisPeter J. FriendChristina YapSimon C. AffordDarius F. MirzaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hynek Mergental
Richard W. Laing
Amanda J. Kirkham
M. Thamara P. R. Perera
Yuri L. Boteon
Joseph Attard
Darren Barton
Stuart Curbishley
Manpreet Wilkhu
Desley A. H. Neil
Stefan G. Hübscher
Paolo Muiesan
John R. Isaac
Keith J. Roberts
Manuel Abradelo
Andrea Schlegel
James Ferguson
Hentie Cilliers
Julian Bion
David H. Adams
Chris Morris
Peter J. Friend
Christina Yap
Simon C. Afford
Darius F. Mirza
Transplantation of discarded livers following viability testing with normothermic machine perfusion
description The shortage of viable donated livers limits patient access to liver transplantation. Here the authors report the use of normothermic machine perfusion to help identify viable organs from livers discarded based on current clinical criteria, which are then transplanted to recipients in a single-arm clinical trial.
format article
author Hynek Mergental
Richard W. Laing
Amanda J. Kirkham
M. Thamara P. R. Perera
Yuri L. Boteon
Joseph Attard
Darren Barton
Stuart Curbishley
Manpreet Wilkhu
Desley A. H. Neil
Stefan G. Hübscher
Paolo Muiesan
John R. Isaac
Keith J. Roberts
Manuel Abradelo
Andrea Schlegel
James Ferguson
Hentie Cilliers
Julian Bion
David H. Adams
Chris Morris
Peter J. Friend
Christina Yap
Simon C. Afford
Darius F. Mirza
author_facet Hynek Mergental
Richard W. Laing
Amanda J. Kirkham
M. Thamara P. R. Perera
Yuri L. Boteon
Joseph Attard
Darren Barton
Stuart Curbishley
Manpreet Wilkhu
Desley A. H. Neil
Stefan G. Hübscher
Paolo Muiesan
John R. Isaac
Keith J. Roberts
Manuel Abradelo
Andrea Schlegel
James Ferguson
Hentie Cilliers
Julian Bion
David H. Adams
Chris Morris
Peter J. Friend
Christina Yap
Simon C. Afford
Darius F. Mirza
author_sort Hynek Mergental
title Transplantation of discarded livers following viability testing with normothermic machine perfusion
title_short Transplantation of discarded livers following viability testing with normothermic machine perfusion
title_full Transplantation of discarded livers following viability testing with normothermic machine perfusion
title_fullStr Transplantation of discarded livers following viability testing with normothermic machine perfusion
title_full_unstemmed Transplantation of discarded livers following viability testing with normothermic machine perfusion
title_sort transplantation of discarded livers following viability testing with normothermic machine perfusion
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/c280eba6b1264d549b001554a3c7ab18
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