CHARACTERISTIC INFLUENCE OF PULSE ELECTROTHERAPY (ELECTRICAL SLEEP) AT A NEUROPEPTIDE-CYTOKINE LINKS IN ARTERIAL HYPERTENSION ACCOMPANIED BY A ASTHENONEUROTIC DISTURBANCES IN YOUNG MEN EMPLOYED IN STRESSFUL PROFESSIONS

Disorders in functioning of major regulatory systems in patients with somatic diseases required development of new and effective integrated approaches to their treatment and prevention. Effective electrotherapy (electrical sleep) is among these methods. Despite existence of studies proving high effi...

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Autores principales:	A. V. Gertsev, V. N. Ischuk
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2018
Materias:	electrosonotherapy electrical sleep hypertension asthenia β-endorphin cytokines Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/c2862ebddcb243cea5f814d5dbd01c49
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spelling	oai:doaj.org-article:c2862ebddcb243cea5f814d5dbd01c492021-11-18T08:03:47ZCHARACTERISTIC INFLUENCE OF PULSE ELECTROTHERAPY (ELECTRICAL SLEEP) AT A NEUROPEPTIDE-CYTOKINE LINKS IN ARTERIAL HYPERTENSION ACCOMPANIED BY A ASTHENONEUROTIC DISTURBANCES IN YOUNG MEN EMPLOYED IN STRESSFUL PROFESSIONS1563-06252313-741X10.15789/1563-0625-2018-1-123-128https://doaj.org/article/c2862ebddcb243cea5f814d5dbd01c492018-01-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/1439https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XDisorders in functioning of major regulatory systems in patients with somatic diseases required development of new and effective integrated approaches to their treatment and prevention. Effective electrotherapy (electrical sleep) is among these methods. Despite existence of studies proving high efficiency of electrical sleep results in therapeutic practice, some open questions remain concerning impact of this treatment upon neuropeptide-cytokine links of immune system, which is one of the most important effector of pathogenesis in cardiovascular diseases in young persons with hypertension from the group occupied with stressful jobs. In this connection, the aim of our study was to investigate the influence on electrical sleep upon neuropeptide-cytokine profile in arterial hypertension conditions accomplished by asthenic-neurotic disorders in young men from the group of stressful activities. The following treatment groups were formed: 1st (n = 12), antihypertensive therapy; 2nd (n = 10), complex therapeutic measures added to antihypertensive therapy plus minor tranquilizers; in the 3rd group (n = 12), electric sleep was performed. Neuropeptide-cytokine profile was investigated as serum contents of β-endorphin, proinflammatory (TNFα, IL-1β, IL-6) and anti-inflammatory (IL-4, IL-10) cytokines. In the course of the clinical and laboratory examination, the authors have found that electric sleep applied in a complex primary schedule, with antihypertensive drug treatment in patients with hypertension and asthenic-neurotic disorders proved to exert optimizing effect upon functioning of neuropeptide-cytokine pool of immune system, which manifested by stimulation of beta-endorphin production, a decrease via regulation of proinflammatory effectors (TNFα, IL-1β, IL-6), and increased anti-inflammatory cytokines (IL-4, IL-10).A. V. GertsevV. N. IschukSPb RAACIarticleelectrosonotherapyelectrical sleephypertensionastheniaβ-endorphincytokinesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 20, Iss 1, Pp 123-128 (2018)
institution	DOAJ
collection	DOAJ
language	RU
topic	electrosonotherapy electrical sleep hypertension asthenia β-endorphin cytokines Immunologic diseases. Allergy RC581-607
spellingShingle	electrosonotherapy electrical sleep hypertension asthenia β-endorphin cytokines Immunologic diseases. Allergy RC581-607 A. V. Gertsev V. N. Ischuk CHARACTERISTIC INFLUENCE OF PULSE ELECTROTHERAPY (ELECTRICAL SLEEP) AT A NEUROPEPTIDE-CYTOKINE LINKS IN ARTERIAL HYPERTENSION ACCOMPANIED BY A ASTHENONEUROTIC DISTURBANCES IN YOUNG MEN EMPLOYED IN STRESSFUL PROFESSIONS
description	Disorders in functioning of major regulatory systems in patients with somatic diseases required development of new and effective integrated approaches to their treatment and prevention. Effective electrotherapy (electrical sleep) is among these methods. Despite existence of studies proving high efficiency of electrical sleep results in therapeutic practice, some open questions remain concerning impact of this treatment upon neuropeptide-cytokine links of immune system, which is one of the most important effector of pathogenesis in cardiovascular diseases in young persons with hypertension from the group occupied with stressful jobs. In this connection, the aim of our study was to investigate the influence on electrical sleep upon neuropeptide-cytokine profile in arterial hypertension conditions accomplished by asthenic-neurotic disorders in young men from the group of stressful activities. The following treatment groups were formed: 1st (n = 12), antihypertensive therapy; 2nd (n = 10), complex therapeutic measures added to antihypertensive therapy plus minor tranquilizers; in the 3rd group (n = 12), electric sleep was performed. Neuropeptide-cytokine profile was investigated as serum contents of β-endorphin, proinflammatory (TNFα, IL-1β, IL-6) and anti-inflammatory (IL-4, IL-10) cytokines. In the course of the clinical and laboratory examination, the authors have found that electric sleep applied in a complex primary schedule, with antihypertensive drug treatment in patients with hypertension and asthenic-neurotic disorders proved to exert optimizing effect upon functioning of neuropeptide-cytokine pool of immune system, which manifested by stimulation of beta-endorphin production, a decrease via regulation of proinflammatory effectors (TNFα, IL-1β, IL-6), and increased anti-inflammatory cytokines (IL-4, IL-10).
format	article
author	A. V. Gertsev V. N. Ischuk
author_facet	A. V. Gertsev V. N. Ischuk
author_sort	A. V. Gertsev
title	CHARACTERISTIC INFLUENCE OF PULSE ELECTROTHERAPY (ELECTRICAL SLEEP) AT A NEUROPEPTIDE-CYTOKINE LINKS IN ARTERIAL HYPERTENSION ACCOMPANIED BY A ASTHENONEUROTIC DISTURBANCES IN YOUNG MEN EMPLOYED IN STRESSFUL PROFESSIONS
title_short	CHARACTERISTIC INFLUENCE OF PULSE ELECTROTHERAPY (ELECTRICAL SLEEP) AT A NEUROPEPTIDE-CYTOKINE LINKS IN ARTERIAL HYPERTENSION ACCOMPANIED BY A ASTHENONEUROTIC DISTURBANCES IN YOUNG MEN EMPLOYED IN STRESSFUL PROFESSIONS
title_full	CHARACTERISTIC INFLUENCE OF PULSE ELECTROTHERAPY (ELECTRICAL SLEEP) AT A NEUROPEPTIDE-CYTOKINE LINKS IN ARTERIAL HYPERTENSION ACCOMPANIED BY A ASTHENONEUROTIC DISTURBANCES IN YOUNG MEN EMPLOYED IN STRESSFUL PROFESSIONS
title_fullStr	CHARACTERISTIC INFLUENCE OF PULSE ELECTROTHERAPY (ELECTRICAL SLEEP) AT A NEUROPEPTIDE-CYTOKINE LINKS IN ARTERIAL HYPERTENSION ACCOMPANIED BY A ASTHENONEUROTIC DISTURBANCES IN YOUNG MEN EMPLOYED IN STRESSFUL PROFESSIONS
title_full_unstemmed	CHARACTERISTIC INFLUENCE OF PULSE ELECTROTHERAPY (ELECTRICAL SLEEP) AT A NEUROPEPTIDE-CYTOKINE LINKS IN ARTERIAL HYPERTENSION ACCOMPANIED BY A ASTHENONEUROTIC DISTURBANCES IN YOUNG MEN EMPLOYED IN STRESSFUL PROFESSIONS
title_sort	characteristic influence of pulse electrotherapy (electrical sleep) at a neuropeptide-cytokine links in arterial hypertension accompanied by a asthenoneurotic disturbances in young men employed in stressful professions
publisher	SPb RAACI
publishDate	2018
url	https://doaj.org/article/c2862ebddcb243cea5f814d5dbd01c49
work_keys_str_mv	AT avgertsev characteristicinfluenceofpulseelectrotherapyelectricalsleepataneuropeptidecytokinelinksinarterialhypertensionaccompaniedbyaasthenoneuroticdisturbancesinyoungmenemployedinstressfulprofessions AT vnischuk characteristicinfluenceofpulseelectrotherapyelectricalsleepataneuropeptidecytokinelinksinarterialhypertensionaccompaniedbyaasthenoneuroticdisturbancesinyoungmenemployedinstressfulprofessions
_version_	1718422378996826112

CHARACTERISTIC INFLUENCE OF PULSE ELECTROTHERAPY (ELECTRICAL SLEEP) AT A NEUROPEPTIDE-CYTOKINE LINKS IN ARTERIAL HYPERTENSION ACCOMPANIED BY A ASTHENONEUROTIC DISTURBANCES IN YOUNG MEN EMPLOYED IN STRESSFUL PROFESSIONS

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