Protein cages, rings and tubes: useful components of future nanodevices?

Jonathan G HeddleGlobal Edge Institute, Tokyo Institute of Technology, Nagatsuda, Midori-ku, Yokohama Kanagawa, JapanAbstract: There is a great deal of interest in the possibility that complex nanoscale devices can be designed and engineered. Such devices will lead to the development of new material...

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Autor principal:	Jonathan G Heddle
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2008
Materias:	Medical technology R855-855.5 Chemical technology TP1-1185
Acceso en línea:	https://doaj.org/article/c288aed1d06a4f7c9f95d85036ddf429
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spelling	oai:doaj.org-article:c288aed1d06a4f7c9f95d85036ddf4292021-12-02T00:35:45ZProtein cages, rings and tubes: useful components of future nanodevices?1177-8903https://doaj.org/article/c288aed1d06a4f7c9f95d85036ddf4292008-11-01T00:00:00Zhttp://www.dovepress.com/protein-cages-rings-and-tubes-useful-components-of-future-nanodevices-a2583https://doaj.org/toc/1177-8903Jonathan G HeddleGlobal Edge Institute, Tokyo Institute of Technology, Nagatsuda, Midori-ku, Yokohama Kanagawa, JapanAbstract: There is a great deal of interest in the possibility that complex nanoscale devices can be designed and engineered. Such devices will lead to the development of new materials, electronics and smart drugs. Producing complex nanoscale devices, however will present many challenges and the components of such devices will require a number of special features. Devices will be engineered to incorporate desired functionalities but, because of the difficulties of controlling matter precisely at the nanoscale with current technology, the nanodevice components must self-assemble. In addition, nanocomponents that are to have wide applicability in various devices must have enough flexibility to integrate into a large number of potentially very different environments. These challenges are daunting and complex, and artificial nanodevices have not yet been constructed. However, the existence of nanomachines in nature in the form of proteins (eg, enzymes) suggests that they will be possible to produce. As the material from which nature&rsquo;s nanomachines are made, proteins seem ideal to form the basis of engineered components of such nanodevices. Initially, engineering projects may focus on building blocks such as rings, cages and tubes, examples of which exist in nature and may act as a useful start point for modification and further development. This review focuses on the recent research and possible future development of such protein building blocks.Keywords: bionanotechnology, protein engineering, nanomachine, building-blocks, synthetic biology Jonathan G HeddleDove Medical PressarticleMedical technologyR855-855.5Chemical technologyTP1-1185ENNanotechnology, Science and Applications, Vol 2008, Iss default, Pp 67-78 (2008)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medical technology R855-855.5 Chemical technology TP1-1185
spellingShingle	Medical technology R855-855.5 Chemical technology TP1-1185 Jonathan G Heddle Protein cages, rings and tubes: useful components of future nanodevices?
description	Jonathan G HeddleGlobal Edge Institute, Tokyo Institute of Technology, Nagatsuda, Midori-ku, Yokohama Kanagawa, JapanAbstract: There is a great deal of interest in the possibility that complex nanoscale devices can be designed and engineered. Such devices will lead to the development of new materials, electronics and smart drugs. Producing complex nanoscale devices, however will present many challenges and the components of such devices will require a number of special features. Devices will be engineered to incorporate desired functionalities but, because of the difficulties of controlling matter precisely at the nanoscale with current technology, the nanodevice components must self-assemble. In addition, nanocomponents that are to have wide applicability in various devices must have enough flexibility to integrate into a large number of potentially very different environments. These challenges are daunting and complex, and artificial nanodevices have not yet been constructed. However, the existence of nanomachines in nature in the form of proteins (eg, enzymes) suggests that they will be possible to produce. As the material from which nature&rsquo;s nanomachines are made, proteins seem ideal to form the basis of engineered components of such nanodevices. Initially, engineering projects may focus on building blocks such as rings, cages and tubes, examples of which exist in nature and may act as a useful start point for modification and further development. This review focuses on the recent research and possible future development of such protein building blocks.Keywords: bionanotechnology, protein engineering, nanomachine, building-blocks, synthetic biology
format	article
author	Jonathan G Heddle
author_facet	Jonathan G Heddle
author_sort	Jonathan G Heddle
title	Protein cages, rings and tubes: useful components of future nanodevices?
title_short	Protein cages, rings and tubes: useful components of future nanodevices?
title_full	Protein cages, rings and tubes: useful components of future nanodevices?
title_fullStr	Protein cages, rings and tubes: useful components of future nanodevices?
title_full_unstemmed	Protein cages, rings and tubes: useful components of future nanodevices?
title_sort	protein cages, rings and tubes: useful components of future nanodevices?
publisher	Dove Medical Press
publishDate	2008
url	https://doaj.org/article/c288aed1d06a4f7c9f95d85036ddf429
work_keys_str_mv	AT jonathangheddle proteincagesringsandtubesusefulcomponentsoffuturenanodevices
_version_	1718403645031055360

Protein cages, rings and tubes: useful components of future nanodevices?

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