A minimal model for multiple epidemics and immunity spreading.

Pathogens and parasites are ubiquitous in the living world, being limited only by availability of suitable hosts. The ability to transmit a particular disease depends on competing infections as well as on the status of host immunity. Multiple diseases compete for the same resource and their fate is...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Kim Sneppen, Ala Trusina, Mogens H Jensen, Stefan Bornholdt
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2010
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/c294e82344d344dc8cdb7a005356d430
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c294e82344d344dc8cdb7a005356d430
record_format	dspace
spelling	oai:doaj.org-article:c294e82344d344dc8cdb7a005356d4302021-11-18T07:03:10ZA minimal model for multiple epidemics and immunity spreading.1932-620310.1371/journal.pone.0013326https://doaj.org/article/c294e82344d344dc8cdb7a005356d4302010-10-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20976185/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Pathogens and parasites are ubiquitous in the living world, being limited only by availability of suitable hosts. The ability to transmit a particular disease depends on competing infections as well as on the status of host immunity. Multiple diseases compete for the same resource and their fate is coupled to each other. Such couplings have many facets, for example cross-immunization between related influenza strains, mutual inhibition by killing the host, or possible even a mutual catalytic effect if host immunity is impaired. We here introduce a minimal model for an unlimited number of unrelated pathogens whose interaction is simplified to simple mutual exclusion. The model incorporates an ongoing development of host immunity to past diseases, while leaving the system open for emergence of new diseases. The model exhibits a rich dynamical behavior with interacting infection waves, leaving broad trails of immunization in the host population. This obtained immunization pattern depends only on the system size and on the mutation rate that initiates new diseases.Kim SneppenAla TrusinaMogens H JensenStefan BornholdtPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 5, Iss 10, p e13326 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kim Sneppen Ala Trusina Mogens H Jensen Stefan Bornholdt A minimal model for multiple epidemics and immunity spreading.
description	Pathogens and parasites are ubiquitous in the living world, being limited only by availability of suitable hosts. The ability to transmit a particular disease depends on competing infections as well as on the status of host immunity. Multiple diseases compete for the same resource and their fate is coupled to each other. Such couplings have many facets, for example cross-immunization between related influenza strains, mutual inhibition by killing the host, or possible even a mutual catalytic effect if host immunity is impaired. We here introduce a minimal model for an unlimited number of unrelated pathogens whose interaction is simplified to simple mutual exclusion. The model incorporates an ongoing development of host immunity to past diseases, while leaving the system open for emergence of new diseases. The model exhibits a rich dynamical behavior with interacting infection waves, leaving broad trails of immunization in the host population. This obtained immunization pattern depends only on the system size and on the mutation rate that initiates new diseases.
format	article
author	Kim Sneppen Ala Trusina Mogens H Jensen Stefan Bornholdt
author_facet	Kim Sneppen Ala Trusina Mogens H Jensen Stefan Bornholdt
author_sort	Kim Sneppen
title	A minimal model for multiple epidemics and immunity spreading.
title_short	A minimal model for multiple epidemics and immunity spreading.
title_full	A minimal model for multiple epidemics and immunity spreading.
title_fullStr	A minimal model for multiple epidemics and immunity spreading.
title_full_unstemmed	A minimal model for multiple epidemics and immunity spreading.
title_sort	minimal model for multiple epidemics and immunity spreading.
publisher	Public Library of Science (PLoS)
publishDate	2010
url	https://doaj.org/article/c294e82344d344dc8cdb7a005356d430
work_keys_str_mv	AT kimsneppen aminimalmodelformultipleepidemicsandimmunityspreading AT alatrusina aminimalmodelformultipleepidemicsandimmunityspreading AT mogenshjensen aminimalmodelformultipleepidemicsandimmunityspreading AT stefanbornholdt aminimalmodelformultipleepidemicsandimmunityspreading AT kimsneppen minimalmodelformultipleepidemicsandimmunityspreading AT alatrusina minimalmodelformultipleepidemicsandimmunityspreading AT mogenshjensen minimalmodelformultipleepidemicsandimmunityspreading AT stefanbornholdt minimalmodelformultipleepidemicsandimmunityspreading
_version_	1718424005539528704

A minimal model for multiple epidemics and immunity spreading.

Ejemplares similares