CD300f:IL-5 cross-talk inhibits adipose tissue eosinophil homing and subsequent IL-4 production
Abstract Eosinophils and their associated cytokines IL-4 and IL-5 are emerging as central orchestrators of the immune-metabolic axis. Herein, we demonstrate that cross-talk between the Ig-superfamily receptor CD300f and IL-5 is a key checkpoint that modifies the ability of eosinophils to regulate me...
Enregistré dans:
Auteurs principaux: | Perri Rozenberg, Hadar Reichman, Israel Zab-Bar, Michal Itan, Metsada Pasmanik-Chor, Carine Bouffi, Udi Qimron, Ido Bachelet, Patricia C. Fulkerson, Marc E. Rothenberg, Ariel Munitz |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/c2a3e62ec5e140ed9d6934d68101ee2c |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Transcriptome profiling of mouse colonic eosinophils reveals a key role for eosinophils in the induction of s100a8 and s100a9 in mucosal healing
par: Hadar Reichman, et autres
Publié: (2017) -
Rapid seroconversion and persistent functional IgG antibodies in severe COVID-19 patients correlates with an IL-12p70 and IL-33 signature
par: Ariel Munitz, et autres
Publié: (2021) -
Myeloid-IL4Rα is an indispensable link in IL-33-ILCs-IL-13-IL4Rα axis of eosinophil recruitment in murine lungs
par: Sonika Patial, et autres
Publié: (2021) -
Lung eosinophils elicited during allergic and acute aspergillosis express RORγt and IL-23R but do not require IL-23 for IL-17 production.
par: Bhawna Yadav, et autres
Publié: (2021) -
ROLE OF IL-5 AND EOTAXIN IN DEVELOPMENT OF BLOOD EOSINOPHILIC REACTION DURING PULMONARY TUBERCULOSIS
par: U. V. Kolobovnikova, et autres
Publié: (2014)