A 5 year retrospective analysis of adverse drug reactions associated with antimicrobials in a teaching hospital of Andaman and Nicobar islands

Antimicrobials are used widely especially in developing countries, due to the high prevalence of various infectious diseases. Inappropriate use of antimicrobials are associated with adverse drug reactions. The present study was done to analyze the patterns of Adverse Drug Reactions (ADR) due to anti...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mangesh Bankar, Priyanka Pravinbhai Hotha, Nimisha Elezebeth Zachariah
Formato:	article
Lenguaje:	EN
Publicado:	Universitas Ahmad Dahlan 2021
Materias:	adverse drug reaction antimicrobial drugs pharmacovigilance ceftriaxone Pharmacy and materia medica RS1-441
Acceso en línea:	https://doaj.org/article/c2a5851b97f149f485badcba4460fff6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c2a5851b97f149f485badcba4460fff6
record_format	dspace
spelling	oai:doaj.org-article:c2a5851b97f149f485badcba4460fff62021-11-17T06:51:46ZA 5 year retrospective analysis of adverse drug reactions associated with antimicrobials in a teaching hospital of Andaman and Nicobar islands10.12928/pharmaciana.v11i3.208662088-45592477-0256https://doaj.org/article/c2a5851b97f149f485badcba4460fff62021-11-01T00:00:00Zhttp://journal.uad.ac.id/index.php/PHARMACIANA/article/view/20866/pdf_209https://doaj.org/toc/2088-4559https://doaj.org/toc/2477-0256Antimicrobials are used widely especially in developing countries, due to the high prevalence of various infectious diseases. Inappropriate use of antimicrobials are associated with adverse drug reactions. The present study was done to analyze the patterns of Adverse Drug Reactions (ADR) due to antimicrobials reported to Adverse Drug Reaction Monitoring Centre (AMC) during the last five years. This was a 5 year retrospective and cross-sectional study. After collecting demographic details of patients, ADR forms, and ADR associated with the antimicrobial class of drugs, data were analyzed for further details. A total of 877 ADRs, 360 ADRs belonged to the antimicrobial group. When data was analyzed data, it revealed that the majority of ADRs (73.05%) were reported in the adult group, 75.27% of reactions belonged to A category, Ceftriaxone (17.2%) was the most common drug-associated with ADRs, majority of ADRs were related to skin (56.66%), rash (27.5%) was the most common ADR encountered with antimicrobial use, 73.61% reactions were non-serious, 69.44% of ADRs recovered, and 77.77% of ADRs were probable category. Ceftriaxone was responsible for the maximum number of ADRs. The study results provide information regarding the pattern of ADRs associated with antimicrobials, and this might be helpful for improving the awareness of healthcare providers about PvPI and subsequently increase the spontaneous reporting of ADRs.Mangesh BankarPriyanka Pravinbhai Hotha Nimisha Elezebeth ZachariahUniversitas Ahmad Dahlanarticleadverse drug reactionantimicrobial drugspharmacovigilanceceftriaxonePharmacy and materia medicaRS1-441ENPharmaciana, Vol 11, Iss 3, Pp 366-375 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	adverse drug reaction antimicrobial drugs pharmacovigilance ceftriaxone Pharmacy and materia medica RS1-441
spellingShingle	adverse drug reaction antimicrobial drugs pharmacovigilance ceftriaxone Pharmacy and materia medica RS1-441 Mangesh Bankar Priyanka Pravinbhai Hotha Nimisha Elezebeth Zachariah A 5 year retrospective analysis of adverse drug reactions associated with antimicrobials in a teaching hospital of Andaman and Nicobar islands
description	Antimicrobials are used widely especially in developing countries, due to the high prevalence of various infectious diseases. Inappropriate use of antimicrobials are associated with adverse drug reactions. The present study was done to analyze the patterns of Adverse Drug Reactions (ADR) due to antimicrobials reported to Adverse Drug Reaction Monitoring Centre (AMC) during the last five years. This was a 5 year retrospective and cross-sectional study. After collecting demographic details of patients, ADR forms, and ADR associated with the antimicrobial class of drugs, data were analyzed for further details. A total of 877 ADRs, 360 ADRs belonged to the antimicrobial group. When data was analyzed data, it revealed that the majority of ADRs (73.05%) were reported in the adult group, 75.27% of reactions belonged to A category, Ceftriaxone (17.2%) was the most common drug-associated with ADRs, majority of ADRs were related to skin (56.66%), rash (27.5%) was the most common ADR encountered with antimicrobial use, 73.61% reactions were non-serious, 69.44% of ADRs recovered, and 77.77% of ADRs were probable category. Ceftriaxone was responsible for the maximum number of ADRs. The study results provide information regarding the pattern of ADRs associated with antimicrobials, and this might be helpful for improving the awareness of healthcare providers about PvPI and subsequently increase the spontaneous reporting of ADRs.
format	article
author	Mangesh Bankar Priyanka Pravinbhai Hotha Nimisha Elezebeth Zachariah
author_facet	Mangesh Bankar Priyanka Pravinbhai Hotha Nimisha Elezebeth Zachariah
author_sort	Mangesh Bankar
title	A 5 year retrospective analysis of adverse drug reactions associated with antimicrobials in a teaching hospital of Andaman and Nicobar islands
title_short	A 5 year retrospective analysis of adverse drug reactions associated with antimicrobials in a teaching hospital of Andaman and Nicobar islands
title_full	A 5 year retrospective analysis of adverse drug reactions associated with antimicrobials in a teaching hospital of Andaman and Nicobar islands
title_fullStr	A 5 year retrospective analysis of adverse drug reactions associated with antimicrobials in a teaching hospital of Andaman and Nicobar islands
title_full_unstemmed	A 5 year retrospective analysis of adverse drug reactions associated with antimicrobials in a teaching hospital of Andaman and Nicobar islands
title_sort	5 year retrospective analysis of adverse drug reactions associated with antimicrobials in a teaching hospital of andaman and nicobar islands
publisher	Universitas Ahmad Dahlan
publishDate	2021
url	https://doaj.org/article/c2a5851b97f149f485badcba4460fff6
work_keys_str_mv	AT mangeshbankar a5yearretrospectiveanalysisofadversedrugreactionsassociatedwithantimicrobialsinateachinghospitalofandamanandnicobarislands AT priyankapravinbhaihotha a5yearretrospectiveanalysisofadversedrugreactionsassociatedwithantimicrobialsinateachinghospitalofandamanandnicobarislands AT nimishaelezebethzachariah a5yearretrospectiveanalysisofadversedrugreactionsassociatedwithantimicrobialsinateachinghospitalofandamanandnicobarislands AT mangeshbankar 5yearretrospectiveanalysisofadversedrugreactionsassociatedwithantimicrobialsinateachinghospitalofandamanandnicobarislands AT priyankapravinbhaihotha 5yearretrospectiveanalysisofadversedrugreactionsassociatedwithantimicrobialsinateachinghospitalofandamanandnicobarislands AT nimishaelezebethzachariah 5yearretrospectiveanalysisofadversedrugreactionsassociatedwithantimicrobialsinateachinghospitalofandamanandnicobarislands
_version_	1718425887293046784

A 5 year retrospective analysis of adverse drug reactions associated with antimicrobials in a teaching hospital of Andaman and Nicobar islands

Ejemplares similares