The WT1-like transcription factor Klumpfuss maintains lineage commitment of enterocyte progenitors in the Drosophila intestine

Notch signaling mediates intestinal enteroblast specification in Drosophila but the molecular mechanism as to how this is regulated is unclear. Here, the authors show that the transcription factor Klumpfuss ensures enteroblast commitment through repression of enteroendocrine cell fate downstream of...

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Autores principales: Jerome Korzelius, Sina Azami, Tal Ronnen-Oron, Philipp Koch, Maik Baldauf, Elke Meier, Imilce A. Rodriguez-Fernandez, Marco Groth, Pedro Sousa-Victor, Heinrich Jasper
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/c2a85d6a3b0f4b718c076a9ad8d66543
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